Gut Bugs and Lilly’s Foundayo Both Help Curb Yo-Yo Diet Effect

As millions of people lose weight on powerful new obesity drugs, most are asking: what comes next? New findings show they have options to combat the dreaded yo-yo effect, including a surprising potential benefit from a humble gut bacteria supplement.

A pair of Eli Lilly & Co. studies released Wednesday showed that while medicine is the best way to keep weight steady, some patients might be able to reduce their dose or switch to a pill. And a small, provocative trial found that a bacteria called Akkermansia muciniphila helped people who’d slimmed down just by dieting keep some weight off.