Max Nisen, Columnist

Alzheimer’s Bust Is Way Beyond a Setback for Biogen

Treating the disease was the focus of its future — and now investors are paying the price.

A big failure clouds a biotech giant’s future, and argues for changes.

Photographer: Scott Eisen/Bloomberg

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A train wreck that everyone sees coming still hurts.

Biogen Inc. announced Thursday that it was discontinuing late-stage studies of its Alzheimer’s medicine aducanumab. That shouldn’t be a huge surprise: Every other drug attempting to treat Alzheimer’s the same way — by targeting the buildup of amyloid beta plaques in the brain — has failed.