Industries

Can AI Drug Development Live Up to the Hype?

Big Pharma is pouring money into tech-devised treatments, but the verdict is out on whether they’ll actually work.

Illustration: Rosa Sawyers for Bloomberg Businessweek

Trying to get medicine approved by the US Food and Drug Administration often feels like buying an expensive lottery ticket, with the uncertain prospect of a reward years away. It takes about a decade and more than $1 billion on average to take a drug through all the stages of clinical trials, and about 90% never get that far.

Part of the problem is the way researchers discover treatments. Until recently, scientists would come up with a hypothesis and run numerous tests to find a chemical capable of shutting down, say, a disease-causing protein. Then they’d run additional tests to see if they could make that drug stronger, safer and longer-lasting — a risky and time-consuming process. Now the pharmaceutical industry is hoping to make the whole program faster and more predictable with artificial intelligence.