Transportation

NHS Rolls Out £1.7 Million Gene Therapy for Sickle Cell Disease

  • Health service in England agrees discount for Vertex’s Casgevy
  • Drug already available for some patients with beta-thalassemia
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One of the world’s most expensive medicines will be used to treat some patients with sickle cell disease in England using the state-funded National Health Service.

The one-time gene-editing therapy Casgevy, developed by Vertex Pharmaceuticals Inc. and Crispr Therapeutics AG, has a list price of £1.7 million ($2.1 million), but England’s drug cost regulator said it has negotiated a lower, undisclosed price.