Novo Nordisk Takes $820 Million Charge on Failed Heart Drug

  • Trial halted after failing to change patients’ blood pressure
  • Study is rare setback for Ozempic maker after obesity success
Leaders With Lacqua: Novo Nordisk CEO Lars Fruergaard Jørgensen
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Novo Nordisk A/S said it will take an impairment of about 5.7 billion Danish kroner ($820 million) after halting a late-stage study of an experimental heart drug it acquired last year.

The Danish drugmaker stopped the trial partway through, after an independent monitoring committee concluded that it hadn’t hit its main goal of changing blood pressure after 12 weeks. The study of more than 600 patients, Clarion-CKD, had looked at the compound ocedurenone in patients with uncontrolled high blood pressure and advanced chronic kidney disease.