Vertex, Crispr Get Second FDA Approval for Gene Therapy

  • New treatment for beta thalassemia to compete with Bluebird
  • FDA approved Casgevy to treat sickle cell disease in December
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The US Food and Drug Administration has approved the first Crispr-based treatment for a second condition, clearing the gene editing therapy for the blood disorder beta thalassemia.

The drug, called Casgevy, is a collaboration between Vertex Pharmaceuticals Inc. and Crispr Therapeutics AG. It was expected to be approved in March, but was cleared early. Casgevy will compete with Zynteglo, a gene therapy for beta thalassemia sold by the biotech company Bluebird Bio Inc.