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Pfizer Shot Generated Most Antibodies in Comparative Study

  • Breakthrough infection may be more common after Sinopharm shot
  • AstraZeneca vaccine provided ‘intermediate’ protection
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Explain This: How mRNA Covid Vaccines Work
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Pfizer Inc. and BioNTech SE’s Covid-19 shot yielded the strongest immune response among four vaccines tested in a study, which found people getting Sinopharm’s inoculation may be particularly susceptible to a breakthrough infection.

Levels of protective antibodies to the part of the coronavirus that SARS-CoV-2 uses to infect human cells varied widely across each of the four vaccine groups. “Relatively low” antibody concentrations were stimulated by the Sinopharm and Sputnik V vaccines, intermediate levels for the AstraZeneca Plc vaccine, and the highest values for the Pfizer-BioNTech vaccine, a study in the journal Cell Host and Microbe showed.