After $62 Billion Shire Win, Takeda CEO Faces More Headaches

  • Takeda is completing deal with about $31 billion of loans
  • Purchase gives it lucrative new drugs and bigger U.S. presence
Christophe WeberPhotographer: Tomohiro Ohsumi/Bloomberg
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Takeda Pharmaceutical Co.’s Chief Executive Officer Christophe Weber navigated rebuffs, critics and a plunging stock price to win a $62 billion deal to acquire larger rival Shire Plc.

Integrating the Japanese drugmaker -- which began by selling herbal therapies 237 years ago -- with the sprawling American company will be even more complicated.