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Male Sex Drive Depends on Both Estrogen and Testosterone

Estrogen, the main sex hormone in women, plays a bigger role in male libido than previously thought, according to research that may guide development of sex-drive treatments.

The study found that reducing estrogen in men undergoing treatment for low testosterone resulted in a drop in libido and an increase in body fat, even as testosterone levels improved. The research is published in the New England Journal of Medicine.