Gene Tied to Down Syndrome May Suggest Way to New Therapy

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Scientists have identified a gene on the extra chromosome causing Down syndrome that may be responsible for the early aging and cognitive defects in people with the condition, a finding that could lead to new treatments.

The gene, called Usp16, may hinder the body’s ability to make stem cells needed to maintain tissues and organs, according to research published today in the journal Nature. That includes development of organs such as the brain while in the uterus, said Michael Clarke, a senior study author.