Titan Falls After Implant Dose Questioned: San Francisco Mover
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Titan Pharmaceuticals Inc. plunged the most in four years after U.S. regulators questioned whether the company showed the dosages tested of experimental Probuphine implant offered enough benefit to gain approval.
The shares of South San Francisco, California-based Titan fell 42 percent to $1.19 at 4 p.m. New York time for their biggest drop since December 2008. Patient response to the treatment, for treating addiction to heroin and prescription opioid painkillers, indicate that doses may not have been “high enough” in the studies, Food and Drug Administration staff said today in a report.