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Female Biological Clock Runs Out as Egg Repair Genes Wane

Scientists have found a possible reason why women lose their fertility in middle age, in a discovery that could pave the way for treatments to extend women’s childbearing years beyond what is naturally possible.

In a series of experiments on eggs from women getting fertility treatments, researchers learned that the function of several DNA repair genes weaken with age. This decline is accelerated in women near the end of their childbearing years, according to the results published in the journal Science Translational Medicine.