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Adult Migraine Medicines Don’t Help Children, Study Finds

Medicines to prevent or treat migraines in adults aren’t effective in stopping the headaches in children, according to two studies that suggest doctors may want to re-evaluate the use of the drugs in pediatric patients.

An analysis of 21 trials published in JAMA Pediatrics showed that Johnson and Johnson’s seizure medicine Topamax and the antidepressant trazodone “have limited evidence” to support use in children’s migraines occurring fewer than 15 times a month. Other drugs, including some medicines for hypertension are no better than a placebo, the research found.