AIDS Vaccine Sleuths Find New Clues as 30-Year Hunt Continues

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AIDS researchers found clues that help explain why an HIV vaccine worked better for some people than others in a study, advancing scientists’ understanding of the virus.

Researchers identified two genetic “signatures” in the virus among people who contracted HIV despite being vaccinated in a 2009 trial in Thailand. Those genetic features may have helped the virus to evade the vaccine, according to the U.S. Military HIV Research Program in Silver Spring, Maryland, which published the findings today in the journal Nature. The study is also being presented at an AIDS conference in Boston.