Magic Mushrooms May Help Treat Depression, U.K. Researchers Say

Lock
This article is for subscribers only.

Psilocybin, the active ingredient in so-called magic mushrooms, may help people with depression, based on two studies that suggest that the drug could have an enduring effect on patients.

In a study published today in the Proceedings of the National Academy of Sciences, 30 healthy volunteers took psilocybin intravenously and had their brains observed with magnetic resonance imaging scanners. Activity in the medial prefrontal cortex, which is hyperactive in depression, was consistently lowered, according to the research led by David Nutt and Robin Carhart-Harris of Imperial College London.