May 28, 2018 7:01 AM ET

Healthcare Providers and Services

Company Overview of IGeneX, Inc.

Company Overview

IGeneX, Inc. owns and operates a specialty immunology laboratory and research facility. It develops laboratory assays for Lyme and other tick-borne diseases. The company’s laboratory also functions as a pilot site for diagnostic manufacturers in the introduction of new assays. It serves private practice physicians, hospitals, and other clinical reference laboratories in the United States and Canada. IGeneX, Inc. was founded in 1991 and is based in Palo Alto, California.

795 San Antonio Road

Palo Alto, CA 94303

United States

Founded in 1991





Key Executives for IGeneX, Inc.

Compensation as of Fiscal Year 2017.

IGeneX, Inc. Key Developments

IGeneX, Inc. Introduces New Diagnostic Tests for Lyme Disease and Tick-Borne Relapsing Fever

IGeneX Inc. announced the launch of three new tests that are more inclusive and specific for aiding in diagnosis of Borreliosis (Lyme Disease and Tick-Borne Relapsing Fever, Borreliosis). Lyme ImmunoBlotIgM and IgG; Lyme ImmunoBlotIgM and IgGTBRF ImmunoBlot IgM and IgG; Lyme ImmunoBlotIgM and IgGTBRF ImmunoBlot IgM and IgGLyme IGX Spot; Lyme ImmunoBlotIgM and IgGTBRF ImmunoBlot IgM and IgGLyme IGX Spot. Lyme ImmunoBlots IgM and IgG: Although IGeneX Lyme Western blot prepared from Borrelia burgdorferi strains B31 and 297 is one of the most sensitive tests, it does not detect antibodies to all the B. burgdorferi sensu lato antigens. To develop all inclusive Western blots would be very expensive and impractical. Therefore, IGeneX has developed a Lyme ImmunoBlot that is very specific and inclusive of most species of B. burgdorferi sensu lato for clinical use with the following advantages over a Western blot: The specificity of the ImmunoBlot is 98.0% for IgM and 98.7% for IgG. This is higher than the traditional Western Blot; The 31kDa Epitope confirmation test will not be required on patient samples tested by Lyme ImmunoBlots; The sensitivity of the Lyme Immunoblot is 90.9% with well-defined samples. TBRF ImmunoBlots IgM and IgG: The TBRF ImmunoBlot is designed to detect antibodies to specific antigens of TBRF Borrelia in human serum. It detects antibodies to B. hermsii, B. miyamotoi, B. turicatae and B. coriaceae. Based on in-house studies these blots detect antibodies to North American, European and Australian strains of TBRF Borrelia in patient serum samples. The specificity of the TBRF ImmunoBlot is 94% and 98% for IgM and IgG respectively. Lyme IGX Spot: The LymeIGXSpot is an Enzyme-Linked ImmunoSpot (ELISPOT) assay that detects human T cells reactive to B. burgdorferi specific antigens in vitro. ELISPOT is a widely used method for detecting and monitoring cellular immune responses to specific antigens.

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