January 22, 2018 4:14 PM ET

Biotechnology

Company Overview of X-Chem, Inc.

Company Overview

X-Chem, Inc. operates independently of Pharmaceutical Product Development, LLC as of January 06, 2016.

100 Beaver Street Suite 101

Waltham, MA 02453

United States

Phone:

781-419-6900

Fax:

781-419-6903

Key Executives for X-Chem, Inc.

X-Chem, Inc. does not have any Key Executives recorded.

X-Chem, Inc. Key Developments

X-Chem Enters Expanded Global Drug Discovery and Technology Transfer Collaboration with Astrazeneca

X-Chem, Inc. announced a significant expansion of their existing global drug discovery collaboration with the global biopharmaceutical company AstraZeneca. The new agreement focuses on the synthesis and delivery of custom libraries to AstraZeneca as well as the transfer of the DEX platform, allowing for in-house screening of DNA-encoded libraries at AstraZeneca. It is the third agreement between AstraZeneca and X-Chem since 2012 and builds on the success of the parties’ existing collaboration, which has resulted in numerous licenses to novel small molecules across multiple discovery programs and therapeutic indications to date. Under the terms of the agreement, X-Chem will receive upfront technology access and license fees, as well as multi-year committed funding. X-Chem is also eligible for additional payments linked to the exercise of specific technology transfer options and the achievement of certain R&D and commercial milestones. In addition, X-Chem will receive royalties for each successfully commercialized drug that results from joint target-based collaboration programs.

X-Chem, Inc. Presents at BIO One-on-One Partnering™, Jan-07-2018

X-Chem, Inc. Presents at BIO One-on-One Partnering™, Jan-07-2018 . Venue: San Francisco, California, United States.

X-Chem, Inc. and Abilita Bio, Inc Announces a Joint Research Collaboration

X-Chem, Inc. and Abilita Bio, Inc. announced a joint research collaboration that will leverage the synergy between each company's platform technology to enable the discovery of novel modulators of high-value G-protein coupled receptors (GPCR) and ion channel targets. Under the terms of the agreement, Abilita will generate EMPsTM for several high-value GPCR and ion-channel targets, which will be screened by X-Chem using its proprietary DEXTM libraries to identify agonists and/or antagonists, as dictated by the target biology and desired mechanism of action. The most promising drug leads resulting from these activities will be selected for further development and commercialization by the parties.

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