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00:00I want to focus on the vaccine potential that the US ordered 100 million of these doses from Pfizer. They say that they could make more than a billion doses by the end of 2021. Walk me through a realistic timeline . Well well I think that's a great question. We've got a number of vaccine candidates in fact that are in the running right now and are in the final stretches where we're planning on having the feast. We efficacy trials entering the fall. So some of them are starting up at the end of this month. But by fall we should be having the Phase 3 which means that we might have efficacy proven for some of these vaccines including the Pfizer vaccine by winter time. And that means that the licensure might be sometime during the winter. Again I'm not sure if that means December January or February but that's the timeframe that I'm looking at. Once we have licensure then of course these manufacturers have to make those doses available. And so we just heard about one hundred million. We hope that those other manufacturers are also going to be successful as well bringing many more millions available throughout the US . What if we can't have a vaccine. Dr. Chen. There was a report yesterday saying that if you catch cold and 19 and you have mild symptoms you have antibodies but they fade really quickly. Are the antibodies that are made by a vaccine different to those . We hope so. We haven't tested that. And that's what we'll be evaluating come this fall with all of these Phase 3 efficacy studies. But it looks like that natural infection the more symptomatic you are the more antibody response is. We're seeing if you have less symptomatic disease or asymptomatic disease you have a much lower antibody response. That's only part of the equation. Scientists also look at a cell mediated immune response which is those seeds for T cells CDC T cells. Those sorts of things are also important in the immune response and may in fact be part of that efficacy that we'll see with either infection or vaccines. Dr. Anthony Bout he was on an ABC affiliate just moments ago talking about treatments likely to come before a vaccine. That seems to make sense when we talk about treatments. Are we talking about something that's going to help you if you're on a ventilator or are we talking treatments like I have it. I want to go in get the pill and I'll feel better . Right. I think that we don't have treatments that are available readily available that are oral treatments right now. The ones that I've been hearing about are mostly the ones that are injectable types for hospitalized patients or they could be taken orally but they're mostly for severely ill patients as well . Nothing like an antibiotic which can be taken as an outpatient for mild disease that I've seen so far. That will be highly efficacious. So we are seeing stepwise improvements with a lot of these drugs that are being evaluated. But again I don't think we have a panacea pill right now . That's a. Can we keep control of the virus. If we have a treatment that works. So yeah. How much worse will it be than flu. If you have a treatment set for the people that are severely ill and then have been critical care they can survive . Yeah that's a good question. I'm not sure. You know we we haven't evaluated all of the different permutations of combination therapies. So we've seen that you know low dose of steroids can be helpful. We've seen that REM disappear can be helpful. But those alone have not shown that we can completely avert hospitalizations and or deaths. It does make a significant improvement in those numbers but it doesn't present a panacea. So I think again as we think through the therapies that we're looking at right now none of them are a cure all that are going to get us completely out of this. They are helpful as tools in the tool box for. Doctors to be able to treat patients that are hospitalized. But again I don't see any of this as a complete cure that will help us avert the disaster that we see impending for this fall and winter. So speaking of the disaster then you are also on the governor's task force for curbing 19 as I said an introduction. Give me a sense sort of how you're advising him to open what not to open how to deal with school in the fall . Right . So we've been giving him the scientific advice and he's been taking it and running with it and he's been a governor that's been readily accepting and in fact eager to hear from the scientists about all of the developments that have been happening. So you know as for our local school systems you know in my county we've already decided that we're going to go with just virtual only for the fall semester. Other jurisdictions throughout the state are taking you know making their decisions even right now this week or next week. So very soon. But going back to our our governor is looking at all this information and the trends nationwide that are showing that we're seeing an uptick in cases. It's driven primarily by those that are aged 20 to 35 years of age. So these are the younger adults that are probably engaging in social gatherings going to bars and restaurants perhaps not adhering of the best to masking universally went together. So again what we're trying to message out to the public about the importance of this .

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Vaccines Are Not Seen as a Cure-All: University of Maryland

Vaccines might have efficacy proof by winter, says University of Maryland School of Medicine Dr. Wilbur Chen, as he discusses potential coronavirus treatments and his input on Maryland’s Covid-19 task force. He speaks on "Bloomberg Markets: European Close." (Source: Bloomberg)

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