How the U.S. Government Botched Its Multibillion-Dollar Plan to Beat Childhood Disease

The U.S. government spent 14 years trying to design the National Children's Study, broad research that would answer medicine's toughest questions about child health. Here's why it failed

NIH Director Francis Collins

Photographer: David Banks/Bloomberg

In the late 1990s, scientists studying children's health pondered crucial questions they couldn’t answer: Conditions as diverse as asthma and autism were increasing in prevalence, with no clear reason why. Many suspected that a child’s early environment—even exposures in the womb—were connected to medical problems that manifested years later. For example, is risk of asthma influenced by the stress a mother experiences during pregnancy? What role does air pollution play? What about diet? Those links proved difficult to study because by the time a child shows signs of asthma, it's too late to take a blood sample during pregnancy, or analyze the air the newborn breathed.

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