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Williams Among Many Who Cracked Jokes While in Depression

When you think of Ellen DeGeneres, Conan O’Brien, David Letterman and Robin Williams, the first word that comes to mind isn’t depression.

But the four comedians have all struggled with the disease suffered by an estimated 350 million people worldwide, according to their own comments or those close to them. Williams, a comedian known for his manic energy, committed suicide Aug. 11 at age 63. He had suffered a period of severe depression, his publicist Mara Buxbaum said in a statement.