Obese, diabetic mice given an experimental drug designed to mimic a hormone with antidiabetic effects improved the health of the animals and extended their lifespan, a study found.
The compound, called AdipoRon, improved sensitivity to insulin and lowered blood sugar levels in mice fed a high-fat diet and in genetically obese mice, according to the study by scientists including Miki Okada-Iwabu, Toshimasa Yamauchi and Masato Iwabu at University of Tokyo. The research is published today in the journal Nature.