A Promising Pill For Male Birth Control

So why are some drugmakers ignoring the research?

Susan Benoff's research on a potential male birth-control pill began with a puzzling case of infertility. A couple had come into the infertility clinic at North Shore University Hospital in Manhasset, N.Y., seeking to conceive a child through in-vitro fertilization. The couple's earlier attempts to have a child, including artificial insemination with the man's sperm, had all failed. The man's sperm and the woman's egg were normal by every measure, yet the test-tube fertilization also failed: In repeated attempts, the man's sperm were unable to penetrate the eggs. "There was zero percent fertilization," says Benoff, the clinic's research molecular biologist, who investigates the clinic's failures. "The couple was upset, and the physicians were upset."

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