Rebuilding The Brain

Cell transplants could lead to revolutionary cures

The white mice scrambling over one another in plastic cages in Dr. Evan Y. Snyder's laboratory at Children's Hospital in Boston look like standard-issue research animals. But they represent a new frontier in the manipulation of life. In a series of recent experiments, Snyder injected living human neurons into the mice's soft, tiny skulls. The neurons survived and spread, sending out connections until they were fully wired into the mice's brains. The mice now negotiate their world with brains that are part human.

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