Now, `Gunsights' For Gene Therapy's Magic Bullets

IN THE FIVE YEARS SINCE DOCTORS BEGAN testing gene therapy, the results have been disappointing. It's easy enough to arm cells with a therapeutic gene and inject them into patients so that the doctored cells will secrete a beneficial product--say, a certain enzyme--into the bloodstream. But it's hard to get sufficient quantities of the enzyme to the sites where it's needed. To date, there have been no cases where gene therapy has definitively saved lives.

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