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Last $116.70 USD
Change Today +2.54 / 2.22%
Volume 768.6K
JAZZ On Other Exchanges
As of 8:10 PM 02/9/16 All times are local (Market data is delayed by at least 15 minutes).
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Company Description

Contact Info

Connaught House

Fourth Floor

One Burlington Road

Dublin, 4


Phone: 353 1 634 7800

Fax: 353 1 634 7850

bution by PHE, which also manufactures the product for it. PHE is the company’s sole supplier for Erwinaze. The company is obligated to make tiered royalty payments to PHE based on worldwide net sales of Erwinaze and Erwinase. Defitelio (defibrotide) / defibrotide Defitelio (defibrotide), a product approved in Europe for the treatment of severe hepatic veno-occlusive disease, or VOD, in adults and children undergoing hematopoietic stem cell transplantation, or HSCT, therapy. Defibrotide, the active pharmaceutical ingredient in Defitelio, is the sodium salt of a complex mixture of single-stranded oligodeoxyribonucleotides derived from porcine DNA. During 2014, Defitelio was launched in a number of European countries. The company promotes Defitelio along with Erwinase to many of the same hematology and oncology specialists. The company owns Gentium S.p.A. (Gentium). The company is also assessing the potential for approval of defibrotide in other countries and for development of defibrotide in indications in addition to the treatment of severe VOD. Prialt (ziconotide) Intrathecal Infusion and Other Products The company also commercializes a portfolio of other products, including Prialt. Prialt is an intrathecally administered infusion of ziconotide, approved by the FDA for the management of severe chronic pain in patients for whom intrathecal therapy is warranted, and who are intolerant of or refractory to other treatment, such as systemic analgesics, adjunctive therapies or intrathecal morphine. Prialt is the only FDA-approved non-opioid intrathecal analgesic. The company has worldwide rights to Prialt, excluding 34 countries outside of the United States licensed by Eisai Co. Limited, or Eisai, from Elan Pharmaceuticals, Inc. (subsequently acquired by Perrigo Company plc) in 2010. The company supplies Prialt to Eisai. Other products the company sells include various psychiatry products in the United States and products in the oncology, critical care and oncology supportive care therapeutic areas, primarily in markets outside of the United States. Research and Development For the year ended December 31, 2014, the company recorded $85.2 million on research and development expenses. Sales and Marketing The company has commercial operations primarily in the United States and Europe. In the United States, its products are marketed through its commercial teams, including approximately 150 trained, experienced sales professionals who promote Xyrem, Erwinaze and Prialt directly to physicians in specialties appropriate for each product. Outside of the United States, its hematology and oncology sales force has approximately 25 hematology field specialists responsible for promoting Erwinase and Defitelio in approved markets where the company commercializes these products. The company’s commercial activities include marketing-related services, distribution services and commercial support services. Customers and Geographic Areas In the United States, the company’s primary marketed product Xyrem is sold to one specialty pharmacy, ESSDS, which ships Xyrem directly to patients. Erwinaze is sold through an exclusive wholesaler and distributor, Accredo Health Group, Inc., to hospitals. Among the other products it commercializes in the United States, Prialt is sold through an exclusive wholesale distributor and pharmacy to medical facilities, while the others are sold primarily to distributors who distribute the product to pharmacies and hospitals. Outside of the United States, the company distributes Erwinase through Durbin PLC, a U.K.-based wholesaler and distributor, to hospitals and local wholesalers in Europe where it markets Erwinase directly and, in markets where it does not market Erwinase directly, to local distributors and wholesalers in Europe and elsewhere in the world. The company distributes Defitelio primarily through IDIS Limited, or IDIS, a U.K. based distributor, to the European countries where the product has been launched commercially. The company also works with IDIS and a number of local distributors in Europe and elsewhere in the world to distribute defibrotide on a named pat


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Valuation JAZZ Industry Range
Price/Earnings 22.7x
Price/Sales 5.3x
Price/Book 4.5x
Price/Cash Flow 16.1x
TEV/Sales 3.6x

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