ICU Medical, Inc. engages in the development, manufacture, and sale of medical devices used in infusion therapy, oncology and critical care applications. The company’s product line includes needlefree connection devices, custom infusion sets, closed system transfer devices (CSTD) for the handling of hazardous drugs, advanced sensor catheters, closed blood sampling systems, and hemodynamic monitoring systems. The company’s products are used in acute care hospitals and ambulatory clinics in approximately 60 countries worldwide. The company categorizes its products into three major market segments, including Infusion Therapy, Critical Care, and Oncology. Products Infusion Therapy Infusion therapy lines, used in hospitals and ambulatory clinics, consist of a tube running from a bottle or plastic bag containing a solution to a catheter inserted in a patient’s vein. The tube has various injection ports or Y-sites (conventionally, entry tubes covered by rubber caps) to which a secondary infusion line could be connected to permit constant intravenous administration (I.V.) of medications, fluids and nutrients, and to allow I.V. administration of medication. Clave Needlefree Technology Prior to the introduction of needle-safe connectors, a conventional infusion line terminated with a male luer connector to which a hollow-bore needle would be attached to penetrate an injection port to make a primary or secondary connection. With the Clave technology, instead of attaching a hollow-bore needle to the male luer, the male luer without a needle is attached directly to the needlefree Clave port. All types of medications could be administered through the Clave by using a standard syringe or various types of administration sets. The Clave could be used with any conventional peripheral or central vascular access device, both for venous and arterial applications. The resilience of the silicone compression seal permits repeated connections and disconnections without replacing the Clave. The Clave contains no natural rubber latex. The MicroClave is smaller than the standard Clave but is functionally similar. The MicroClave has a feature where upon disconnection of an infusion set or syringe, there is a neutral displacement of fluid. This allows clinicians to utilize known protocols without the risk of device failure and a saline flush regimen, which reduces cost and exposure to the drug heparin. The MicroClave is intended for use on all peripheral and central catheters, which allow it to be used throughout the hospital and reduce line items that the hospital might need to carry and the educational burden of having multiple devices. The MicroClave Clear is functionally identical to the MicroClave, and has a clear housing so that clinicians could visualize the fluid path. The NanoClave is a derivative of the MicroClave, where it is incorporated into custom manifolds and components to be used in customized applications generally found in neonatal and pediatric patient populations. The NanoClave is also a neutral displacement connector with a clear housing, allowing clinicians to flush the connector clear of medications and blood with minimal flush volumes. Neutron The Neutron catheter patency device also features Clave technology, but includes a bi-directional silicone bellows that helps prevent blood reflux into a catheter to minimize the incidence of occlusion, or blocking of the catheter due to a blood clot. The Neutron is primarily designed to be used on patients receiving longer indwelling central venous catheters. Tego The Tego is a needlefree hemodialysis connector that creates a mechanically and microbiologically closed system when attached to the hub of a catheter, eliminating open catheter hubs and lowering the chance of bacterial contamination and infection. SwabCap SwabCap is a disposable cap designed to disinfect needlefree connectors with 70% isopropyl alcohol. The SwabCap product line complements the Clave family of needlefree connectors, as both work together to deliver the critical elements of safety, protection and maintenance of I.V. catheters. Custom Infusion Sets The compan
icu medical inc (ICUI:NASDAQ GS)
951 Calle Amanecer
San Clemente, CA 92673
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