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Last $0.68 USD
Change Today +0.003 / 0.44%
Volume 53.5K
IBIO On Other Exchanges
As of 8:04 PM 10/12/15 All times are local (Market data is delayed by at least 15 minutes).
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Company Description

Contact Info

9 Innovation Way

Suite 100

Newark, DE 19711

United States

Phone: 302-355-0650


iBio, Inc., a biotechnology company, focuses on commercializing its proprietary platform technologies, iBioLaunch and iBioModulator, and developing select product candidates derived from these platforms. iBioLaunch is a proprietary, transformative platform technology for the development and production of biologics using transient gene expression in hydroponically grown, unmodified green plants. iBioModulator is a proprietary technology platform that is designed to improve the potency and duration of effect of both prophylactic and therapeutic vaccines produced with any recombinant expression technology, including iBioLaunch. The company developed its iBioModulator technology based on the use of a modified form of the cellulose degrading enzyme lichenase from Clostridium thermocellum, a thermophilic and anaerobic bacterium. In addition to the clinical development of the company's vaccine candidates, the U.S. Department of Defense is sponsoring the development of an iBioLaunch-produced anthrax vaccine, and Bio-Manguinhos/FioCruz (FioCruz), a unit of the Oswaldo Cruz Foundation, a central agency of the Ministry of Health of Brazil, is sponsoring the development of an iBioLaunch-produced yellow fever vaccine to replace the vaccine it makes in chicken eggs for the populations of Brazil and approximately 20 other nations. Product Candidates Therapeutic Protein Product Candidates Using iBioLaunch, the company has expressed and demonstrated the feasibility of production of various classes of therapeutic proteins. Recombinant Forms of Plasma Derived Products Using iBioLaunch, the company has produced human C1 esterase inhibitor and human alpha 1-antitrypsin, each of which is important therapeutic products that have been derived from human blood plasma. Other Therapeutic Proteins In addition to the recombinant form of plasma derived products, using iBioLaunch, the company has been able to express and demonstrate the feasibility of production of various other classes of therapeutic proteins. The therapeutic proteins that the company has produced range from large and complex monoclonal antibodies to smaller proteins, such as interferons, growth factors, and enzymes. All the candidate therapeutic proteins manufactured using iBioLaunch have assembled correctly assembled and demonstrated full activity in relevant bioassays. The company is evaluating various potential proprietary iBioLaunch produced therapeutic protein candidates for further development internally at the company or together with collaborators. Vaccine Candidates The company has used iBioLaunch to express and demonstrate the feasibility of production of a range of vaccine candidates, including vaccine candidates that have been impossible to produce on a commercially practical basis using conventional manufacturing systems. Additionally, it has used iBioModulator to improve the performance of therapeutic vaccine candidates. The company’s collaborator, FioCruz, is advancing the development of an iBioLaunch-produced yellow fever vaccine candidate. Biodefense Countermeasures In addition to the company’s demonstration of the feasibility of iBioLaunch produced monoclonal antibody candidates for the treatment of anthrax, next generation anthrax vaccine candidates derived from the iBioLaunch platform are being developed by the company’s collaborator, Fraunhofer Center for Molecular Biology (Fraunhofer), pursuant to a funding award granted to Fraunhofer by the National Institute of Allergy and Infectious Diseases. Strategic Alliances and Collaborations The company has a global alliance with GE Healthcare to commercialize the company’s plant-based technologies for the manufacture of biopharmaceuticals and vaccines. In 2013, the company entered into a license with Caliber Biotherapeutics LLC (Caliber), a for-profit biotechnology company that is focused on the development and commercialization of therapeutic proteins. This license to Caliber is for use of the iBioLaunch platform in connection with the development of an undisclosed monoclonal antibody-based therapeutic protein for an oncology indication. Strategy The company’s strategy to engage in partnering and out-licensing of its technology platforms seeks to preserve the opportunity for the company to share in the development and commercialization of product candidates by its licensees while improving its own capital and financial resources for development, alone or through commercial alliances with others, of high-potential product candidates derived from its platforms. Intellectual Property The company owns 15 U.S. patents and 28 international patents. It also has 3 international patent applications allowed, as well as 10 U.S. and 26 international applications pending. International patents and applications include various foreign countries, including Australia, Brazil, Canada, China, Hong Kong, India, Korea, and various countries in Europe. It continues to prepare patent applications relating to its expanding technology in the U.S. and internationally. Significant Events In October 2014, iBio, Inc. and Novici Biotech LLC have agreed to broaden their commercial collaboration, focused on antibodies and certain vaccine products, to include iBio's proprietary IBIO-CFB03 product for idiopathic pulmonary fibrosis, systemic sclerosis and other fibrotic diseases. Government Regulation Any products that the company or a licensee manufactures distributes under the FDA approval are subject to continuing regulation by the FDA, including record-keeping requirements and reporting of adverse experiences with the products.


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