Foundation Medicine, Inc., a commercial-stage company, offers products enabled by its molecular information platform to physicians and biopharmaceutical companies. The company’s platform includes proprietary methods and algorithms for analyzing specimens across all types of cancer, and for incorporating that information into clinical care in a concise and user-friendly fashion. Its products provide genomic information about each patient’s individual cancer, enabling physicians to optimize treatments in clinical practice and biopharmaceutical companies to develop targeted oncology therapies. The company’s primary clinical products, FoundationOne for solid tumors, and FoundationOne Heme for blood-based cancers, or hematologic malignancies, including leukemia, lymphoma, myeloma, and many sarcomas and pediatric cancers, are, to its knowledge, the available comprehensive genomic profiles designed for use in the routine care of patients with cancer. The company is continuing to expand its sales force, grow its molecular information knowledgebase, called FoundationCORE, publish scientific and medical advances, foster relationships throughout the oncology community, and develop new clinical and technology products. Proposed Strategic Collaboration In January 2015, the company announced a proposed broad, strategic collaboration with Roche Holdings, Inc., or Roche, and certain of its affiliates, in the field of molecular information for oncology. Strategy The key elements of the company’s strategy include driving awareness and adoption of FoundationOne, FoundationOne Heme, and future products it may develop; empowering the broader cancer community with molecular information; demonstrating the value of its products to patients, physicians, and payors; enabling biopharmaceutical companies to more effectively develop new cancer therapies; and investing in product enhancements and new product innovations. Patents The company’s patent portfolio includes a single issued U.S. patent, pending U.S. provisional and utility applications, and strategically focused corresponding international applications filed via the Patent Cooperation Treaty, and foreign national and regional counterpart applications. Trade Secrets and Trademarks Foundation Medicine, FoundationOne, Interactive Cancer Explorer, Once. And for All, and The Molecular Information Company are all registered trademarks of the company in the United States, and various of these marks are at various stages of the registration process in other countries. ICE 2, FoundationCORE and PatientMatch are also trademarks of the company. Research and Development For the year ended December 31, 2014, the company’s research and development expenses were $30.6 million. Significant Events In June 2015, IMS Health and Foundation Medicine, Inc. announced a collaboration to advance the understanding and effectiveness of precision medicines for treating cancer. In January 2016, Foundation Medicine, Inc. and Mirati Therapeutics, Inc. have entered into a collaboration for the development of a companion diagnostic test for glesatinib in non-small cell lung cancer, or NSCLC. In January 2016, Foundation Medicine, Inc. has announced a three-way collaboration with Horizon Healthcare Services, Inc. and Clinical Outcomes Tracking and Analysis to improve clinical outcomes in the treatment of patients with metastatic, non-small cell lung cancer, or NSCLC. Competition Single-Marker and Hotspot Panel Tests: The company’s competitors include laboratory companies, such as Bio-Reference Laboratories, Inc., Laboratory Corporation of America Holdings, Quest Diagnostics Incorporated, Molecular Health, Caris Life Sciences, Guardant Health, Paradigm, NeoGenomics Laboratories, as well as companies that manufacture or may manufacture diagnostic testing kits, such as Abbott Laboratories, Qiagen N.V. and Sequenom, Inc. History Foundation Medicine, Inc. was founded in 2009. The company was incorporated under the laws of the state of Delaware in 2009.
foundation medicine inc (FMI:NASDAQ GS)
150 Second Street
Cambridge, MA 02141
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