therapy. Diagnostics and Genomics Market The Diagnostics and Clinical Market: A significant part of the company’s clinical diagnostic customers are in pathology labs throughout the world. The company’s automated pathology tissue staining platforms and solutions are used most heavily by the large labs located in hospitals, medical centers, and reference labs. Diagnostics and Genomics Products The company’s products fall into six main areas of work, such as pathology products, specific proteins and flow reagents, target enrichment, cytogenetic research solutions and microarrays, polymerase chain reaction (PCR) and quantitative PCR instrumentation and molecular biology reagents and nucleic acid solutions. Pathology: This area consists of routine clinical solutions for tissue based cancer diagnostics with solutions that comprise antibodies, reagents, instruments and software targeting both primary and advanced cancer diagnostics. The company’s CoverStainer and Artisan based product families target primary cancer diagnostics through Hematoxylin and Eosin staining, as well as Special Stains for additional insights and detection of potentially carcinogenic tissue. In 2013, the company launched its new combined IHC/ISH platform, Dako Omnis. The Dako Omnis and Autostainer based IHC solution and Instant Quality Fluorescence In Situ Hybridization (FISH) (IQFISH) technologies provide tumor typing through investigation of protein and gene expression. Specific Proteins and Flow Reagents: The company’s reagent OEM business is a provider of clinical diagnostic products within the areas of specific proteins for turbidimetry and reagents for flow cytometry. These are sold OEM as customized reagent solutions supplied to top IVD companies or through retail partners. Target Enrichment: The company provides a target enrichment portfolio composed of two main platforms, SureSelect and HaloPlex, both enabling customers to select specific target regions of the genome for sequencing. Customers can customize the company’s products for their regions of interest using the SureDesign software, or they can choose from a range of catalog products, including gene panels for specific applications and Exome designs, which allow analysis of the entire coding sequences of the genome. Cytogenetic Research Solutions and Microarrays: The company provides microarrays for Comparative Genomic Hybridization (CGH), mostly used by customers in cytogenetic laboratories. The arrays allow customers to detect genome-wide copy number alterations, with high levels of resolution (from entire chromosomal copy number changes to specific microdeletions or duplications). The arrays are offered in many formats allowing the customers to choose from different levels of resolution and number of samples per arrays. Arrays can also be customized using the SureDesign software. In addition to the microarrays, the company’s solution includes reagents for sample processing, hardware for reading the microarrays, and software to help users view the data in a meaningful way. In addition to the CGH portfolio, the cytogenetics solution comprises a line of oligonucleotide probes for Fluorescent In Situ Hybridization called SureFISH. Approximately 400 probes are available in the company’s catalog, covering most relevant regions in the genome. Cytogenetic labs can use SureFISH probes to detect specific translocations or copy number changes in samples. Additionally, the company provides a range of microarrays to the research market for different types of applications: gene expression, microRNA, methylation, splice variants, and chromatin immunoprecipitation applications. The company’s solution includes reagents for sample preparation and microarray processing; hardware for sample QC and high-throughput microarray scanning; microarrays on industry-standard 1 inches × 3 inches glass slides for key applications; custom microarray design services; and GeneSpring and CytoGenomics software products for data analysis. PCR and Quantitative PCR Instrumentation and Molecular Biology Reagents: PCR is a standard laboratory method used to amplify the amount of genetic material of
agilent technologies inc (AG8:Frankfurt)
5301 Stevens Creek Boulevard
Santa Clara, CA 95051
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