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Last $136.99 USD
Change Today +1.99 / 1.47%
Volume 2.2M
As of 8:10 PM 08/3/15 All times are local (Market data is delayed by at least 15 minutes).

vertex pharmaceuticals inc (VRTX) Snapshot

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Day High
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52 Week High
08/3/15 - $139.15
52 Week Low
08/13/14 - $84.41
Market Cap
Average Volume 10 Days
Shares Outstanding
Dividend Yield

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vertex pharmaceuticals inc (VRTX) Details

Vertex Pharmaceuticals Incorporated engages in discovering, developing, manufacturing, and commercializing small molecule drugs for patients with serious diseases in specialty markets. The company focuses on developing and commercializing therapies for the treatment of cystic fibrosis (CF); and advancing its research and early-stage development programs. It markets KALYDECO (ivacaftor) to treat patients of six years of age and older with CF who have the mutations in their cystic fibrosis transmembrane conductance regulator (CFTR) gene in the United States, Australia, Canada, and the European Union. The company also provides INCIVEK for the treatment of adults with genotype 1 hepatitis C virus infection. In addition, it is developing CFTR correctors, including lumacaftor in combination with ivacaftor, which has completed Phase III development program; and VX-661 in combination with ivacaftor, which is in Phase III development program. Further, it identifies and develops next-generation CFTR corrector compounds; and is involved in the research and early-stage development programs, including programs in the areas of oncology and neurology. Vertex Pharmaceuticals Incorporated sells its products principally to specialty pharmacy providers and wholesalers in North America, as well as government-owned and supported customers in international markets. The company has collaboration agreements with Cystic Fibrosis Foundation Therapeutics Incorporated; BioAxone Biosciences, Inc.; and Janssen Pharmaceuticals, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

1,830 Employees
Last Reported Date: 02/13/15
Founded in 1989

vertex pharmaceuticals inc (VRTX) Top Compensated Officers

Chairman, Chief Executive Officer and Preside...
Total Annual Compensation: $1.1M
Chief Financial Officer and Executive Vice Pr...
Total Annual Compensation: $650.0K
Chief Medical Officer and Executive Vice Pres...
Total Annual Compensation: $789.1K
Chief Commercial Officer and Executive Vice P...
Total Annual Compensation: $600.0K
Special Counsel to the Chief Executive Office...
Total Annual Compensation: $465.0K
Compensation as of Fiscal Year 2014.

vertex pharmaceuticals inc (VRTX) Key Developments

Vertex Pharmaceuticals Incorporated - Special Call

To provide more information on the approval of ORKAMBI

Vertex Pharmaceuticals Incorporated Announces U.S. Food and Drug Administration Approval of ORKAMBI (lumacaftor/ivacaftor)

Vertex Pharmaceuticals Incorporated announced that the U.S. Food and Drug Administration (FDA) approved ORKAMBI (lumacaftor/ivacaftor), the first medicine to treat the underlying cause of cystic fibrosis (CF) in people ages 12 and older with two copies of the F508del mutation. It is only indicated for these patients, who can be identified with a genetic test. Cystic fibrosis is a rare, life-threatening genetic disease. People with two copies of the F508del mutation represent the large group of people with CF. Of the 30,000 people in the United States with CF, approximately 8,500 ages 12 and older have two copies of the F508del mutation. ORKAMBI will be available for shipment to specialty pharmacies in the United States within days. The approval of ORKAMBI was based on data from two Phase 3 studies (TRAFFIC and TRANSPORT) that enrolled more than 1,100 people with CF ages 12 and older with two copies of the F508del mutation. Patients treated with ORKAMBI experienced statistically significant improvements in lung function. Patients also experienced reductions in pulmonary exacerbations and improvements in body mass index (BMI). The most common adverse events included shortness of breath and/or chest tightness, upper respiratory tract infection (common cold) and gastrointestinal symptoms (including nausea, diarrhea, or gas).

Vertex Pharmaceuticals Incorporated Appoints Sangeeta N. Bhatia as an Independent Director

Vertex Pharmaceuticals Incorporated announced that Sangeeta N. Bhatia, M.D., Ph.D., joined its board of directors as an independent director. Dr. Bhatia was elected to serve a three-year term ending in 2018. Dr. Bhatia is a physician and engineer and has been a professor at the Massachusetts Institute of Technology (MIT) since 2005. She currently serves as the John J. and Dorothy Wilson Professor of Health Sciences at the MIT Institute for Medical Engineering and Science and Electrical Engineering and Computer Science (EECS). She also currently serves as a Biomedical Engineer in the Department of Medicine for Brigham and Women's Hospital, an investigator for the Howard Hughes Medical Institute, a member of the Koch Institute for Integrative Cancer Research at MIT and a member of the Broad Institute.


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Industry Average

Valuation VRTX Industry Range
Price/Earnings NM Not Meaningful
Price/Sales 51.7x
Price/Book 31.5x
Price/Cash Flow NM Not Meaningful
TEV/Sales 49.5x

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