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Last 272.00 GBp
Change Today -13.00 / -4.56%
Volume 28.4K
As of 11:14 AM 04/21/15 All times are local (Market data is delayed by at least 15 minutes).

silence therapeutics plc (SLN) Snapshot

280.00 GBp
Previous Close
285.00 GBp
Day High
280.00 GBp
Day Low
272.00 GBp
52 Week High
03/23/15 - 299.00 GBp
52 Week Low
10/16/14 - 168.00 GBp
Market Cap
Average Volume 10 Days
-0.22 GBp
Shares Outstanding
Dividend Yield

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silence therapeutics plc (SLN) Details

Silence Therapeutics plc, a biotechnology company, discovers, develops, and delivers RNA interference (RNAi) therapeutics for the treatment of serious diseases primarily in North America and the Asia/Pacific. It has AtuRNAi, an RNAi platform, which encompasses the generation of potent chemically stabilized siRNA molecules. The company also has proprietary siRNA delivery technology platforms that comprise AtuPLEX, which delivers siRNA to the endothelial cells of the vascular system; DACC delivery system that delivers siRNA to the vascular endothelial cells of the lung; and DBTC delivery system, which delivers siRNA to hepatocytes and the hepatic vascular system of the liver parenchyma. Its products include Atu027, which is in the Phase IIa clinical trial for the treatment of pancreatic cancer, as well as in the Phase Ib clinical trial for head and neck cancer; Atu111 that is in pre-clinical stage for the treatment of lung diseases; and Atu112, which is in the pre-clinical stage for the treatment of systemic disorders. The company is also developing products for immunotherapy. Silence Therapeutics plc has partnership and collaboration agreements with various pharmaceutical companies, including Pfizer/Quark Pharmaceuticals, Novartis, AstraZeneca, Dainippon Sumitomo Pharma Co., Ltd., InteRNA Technologies B.V., Mirna Therapeutics Inc., and miRagen Therapeutics, Inc. The company was incorporated in 1994 and is based in London, the United Kingdom.

silence therapeutics plc (SLN) Top Compensated Officers

Chief Executive and Director
Total Annual Compensation: 70.0K GBP
Finance Director, Company Secretary and Direc...
Total Annual Compensation: 119.0K GBP
Chief Operating Officer
Total Annual Compensation: 58.0K GBP
Chief Medical Officer and Director
Total Annual Compensation: 53.0K GBP
Compensation as of Fiscal Year 2013.

silence therapeutics plc (SLN) Key Developments

Silence Therapeutics plc Reports Unaudited Consolidated Earnings Results and Company Cash Flow Results for the Full Year Ended December 31, 2014

Silence Therapeutics plc reported unaudited consolidated earnings results and company cash flow results for the full year ended December 31, 2014. For the year, the company reported revenue of £15,000 against £177,000 a year ago. Operating loss was £12,127,000 against £9,072,000 for the same period in the last year. Finance income was £147,000 against £70,000 for the same period in the last year. Loss for the period before taxation was £11,980,000 against £9,002,000 a year ago. Loss for the period after taxation was £11,088,000 against £9,002,000 a year ago. Loss per ordinary equity share (basic and diluted) was 22.0 pence against 20.0 pence a year ago. Net cash outflow from operating activities £9,458,000 against £6,756,000 a year ago. Addition to property, plant and equipment was £337,000 against £120,000 for the same period in the last year. Addition to intangible assets was £1,000 against £18,000 for the same period in the last year. Financial income was higher at £139,000 against £70,000 a year ago mainly due to higher average cash balances during the year.

Silence Therapeutics plc Presents at 8th Annual EUROPEAN LIFE SCIENCE CEO FORUM & EXHIBITION, Mar-03-2015 through Mar-04-2015

Silence Therapeutics plc Presents at 8th Annual EUROPEAN LIFE SCIENCE CEO FORUM & EXHIBITION, Mar-03-2015 through Mar-04-2015. Venue: Hilton, Zurich Airport Hotel, Hohenbuehlstrasse 10, Opfikon-Glattbrugg 8152 Zurich, Zurich, Switzerland. Presentation Date & Speakers: Mar-03-2015, Michael Khan, Chief Medical Officer and Director.

Silence Therapeutics plc Announces Board Changes

Silence Therapeutics plc announced that Simon Sturge and Alastair Riddell will exchange roles. As from the January 5, 2015 Alastair Riddell will take on the role of Non-executive Chairman of the Board and Chair the Nominations Committee. Simon Sturge will remain a Non Executive Director and Chair the Remuneration Committee. Simon Sturge became Non-executive Chairman in November 2013. In March 2014 he was appointed to a senior executive role with Merck KgaA based in Switzerland heading their Biosimilars activity, which has necessarily reduced his availability in UK.


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Industry Average

Valuation SLN Industry Range
Price/Earnings NM Not Meaningful
Price/Sales 9,232.1x
Price/Book 5.0x
Price/Cash Flow NM Not Meaningful
TEV/Sales 9,228.2x

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