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Last $33.76 USD
Change Today -0.44 / -1.29%
Volume 497.7K
RLYP On Other Exchanges
Symbol
Exchange
NASDAQ GS
Berlin
As of 8:10 PM 05/26/15 All times are local (Market data is delayed by at least 15 minutes).

relypsa inc (RLYP) Snapshot

Open
$33.92
Previous Close
$34.20
Day High
$35.00
Day Low
$33.56
52 Week High
03/5/15 - $42.26
52 Week Low
10/15/14 - $17.60
Market Cap
1.4B
Average Volume 10 Days
370.2K
EPS TTM
$-2.66
Shares Outstanding
41.5M
EX-Date
--
P/E TM
--
Dividend
--
Dividend Yield
--
Current Stock Chart for RELYPSA INC (RLYP)

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relypsa inc (RLYP) Details

Relypsa, Inc., a biopharmaceutical company, focuses on the development and commercialization of non-absorbed polymeric drugs to treat disorders in the areas of renal, cardiovascular, and metabolic diseases in the United States. Its lead product candidate includes Patiromer, a non-absorbed potassium binding polymer that completed Phase III clinical trial for the treatment of hyperkalemia. The company was founded in 2007 and is based in Redwood City, California.

145 Employees
Last Reported Date: 05/7/15
Founded in 2007

relypsa inc (RLYP) Top Compensated Officers

Chief Executive Officer, President and Direct...
Total Annual Compensation: $540.1K
Founder
Total Annual Compensation: $172.5K
Chief Medical Officer and Senior Vice Preside...
Total Annual Compensation: $321.9K
Senior Vice President of Pharmaceutical Devel...
Total Annual Compensation: $304.0K
Chief Commercial Officer and Senior Vice Pres...
Total Annual Compensation: $170.8K
Compensation as of Fiscal Year 2014.

relypsa inc (RLYP) Key Developments

Relypsa, Inc. Announces Unaudited Consolidated Earnings Results for the First Quarter Ended March 31, 2015

Relypsa, Inc. announced unaudited consolidated earnings results for the first quarter ended March 31, 2015. For the quarter, net loss was $29,665,000 or $0.78 per basic and diluted share compared to $16,068,000 or $0.54 per basic and diluted share a year ago. Loss from operations was $29,267,000 against $15,704,000 a year ago.

Relypsa, Inc. Presents at Bank of America Merrill Lynch 2015 Health Care Conference, May-12-2015 12:00 PM

Relypsa, Inc. Presents at Bank of America Merrill Lynch 2015 Health Care Conference, May-12-2015 12:00 PM. Venue: Encore at the Wynn, 3131 S Las Vegas Blvd, Las Vegas, Nevada, United States. Speakers: John A. Orwin, Chief Executive Officer, President and Director.

Relypsa Inc. Presents Sub-Group Analysis from Phase 3 Study of Patiromer FOS in Patients with Advanced Chronic Kidney Disease

Relypsa Inc. announced that data from a Phase 3 clinical program showing that Patiromer for Oral Suspension (Patiromer FOS), the company's product candidate, was effective in reducing potassium levels and preventing a recurrence of hyperkalemia in patients with advanced (stage 4-5) chronic kidney disease (CKD) receiving ongoing treatment with renin-angiotensin-aldosterone system (RAAS) inhibitors were presented as a poster at the National Kidney Foundation 2015 Spring Clinical Meeting. The results are from a sub-group analysis of the two part Phase 3 trial, OPAL-HK, conducted under a Special Protocol Assessment with the U.S. Food and Drug Administration. The phase 3 OPAL-HK trial primary outcomes were combined with results from Relypsa's broader clinical development program to support the company's New Drug Application for Patiromer FOS. The FDA has assigned a Prescription Drug User Fee Act (PDUFA) action date of October 21, 2015 for completion of the review of the NDA. Poster #240, entitled 'Patiromer Reduced Recurrent Hyperkalemia in Patients with Advanced CKD on RAAS Inhibitors: results from the randomized Phase 3 OPAL-HK study,' reports that a statistically significant reduction in potassium levels from baseline were observed in 106 patients with stage 4-5 CKD treated with Patiromer FOS during an initial four week treatment phase. Baseline demographics include estimated glomerular filtration rate (eGFR) levels of 21.3 mL/min/1.73 m2, 62% of patients with type 2 diabetes, 97% with hypertension, and 23% with a history of myocardial infarction. Patients had mean Charlson Comorbidity Index (CCI) score of 6.5, consistent with a significant disease burden and high mortality risk. All patients were receiving RAAS inhibitor therapy, including 40% at investigator-determined maximal dose. At the conclusion of the four week treatment phase, 72% of patients had potassium levels within a normal target range. Following the treatment phase, eligible patients underwent an eight week placebo-controlled withdrawal phase in which 69% of placebo patients had at least one recurrent hyperkalemia event (serum potassium = 5.5 mEq/L) versus 20% of Patiromer FOS patients. Additionally, in a pre-specified exploratory analysis, 65% of placebo patients required an adjustment or discontinuation of RAAS inhibitor therapy due to hyperkalemia during the withdrawal phase as compared to 14% of patients treated with Patiromer FOS. Mean levels of calcium and magnesium consistently remained within normal ranges in patients treated throughout both phases of the study. Overall, Patiromer FOS was well tolerated, with a low rate of discontinuations due to adverse events and a low rate of hypokalemia.

 

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