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prometic life sciences inc (PLI) Snapshot

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11/18/14 - C$2.21
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04/29/14 - C$0.85
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prometic life sciences inc (PLI) Details

ProMetic Life Sciences Inc., a biopharmaceutical company, develops bioseparation, plasma-derived therapeutics, and small-molecule drugs. The company also offers its technologies for large-scale drug purification, drug development, proteomics, and the elimination of pathogens; and develops small molecule therapeutics products targeting unmet medical needs in the fields of fibrosis, anemia, cancer, and autoimmune disease, as well as plasma-derived therapeutics in orphan drug indications. It operates in two segments, Therapeutics and Protein Technology. The Therapeutics segment’s lead product includes PBI-4050, which targets unmet medical needs, such as the treatment of fibrosis in patients with chronic kidney diseases and certain cancers, and the side effects associated with chemotherapy. This segment also develops PBI-4419, an anti-fibrotic and anti-inflammatory compound for kidney injury and chronic kidney diseases; and PBI-1402, a drug candidate for the treatment of anemia indications. The Protein Technology segment provides plasma protein purification system, a solution for the extraction and purification of therapeutic proteins from human plasma; bioseparation products based on applications of its patented Mimetic Ligand technology for various biopharmaceutical companies; and prion capture/pathogen removal technology platform that improves the safety profile of blood products and blood-derived therapeutics. The company was formerly known as Innovon Life Sciences Holdings Limited and changed its name to ProMetic Life Sciences Inc. in May 1998. ProMetic Life Sciences Inc. was founded in 1992 and is headquartered in Laval, Canada.

Founded in 1992

prometic life sciences inc (PLI) Top Compensated Officers

Chief Executive Officer, President and Non-In...
Total Annual Compensation: C$435.0K
Chief Financial Officer and Chief Operating O...
Total Annual Compensation: C$322.3K
Chief Executive Officer of ProMetic BioScienc...
Total Annual Compensation: C$238.5K
General Counsel and Corporate Secretary
Total Annual Compensation: C$197.0K
Senior Vice President of Product & Asia Pacif...
Total Annual Compensation: C$283.6K
Compensation as of Fiscal Year 2013.

prometic life sciences inc (PLI) Key Developments

ProMetic Life Sciences Inc. Provides fourth quarter of 2014 Clinical Development and Commercial Milestones Update

ProMetic Life Sciences Inc. provided tan update on its clinical development and commercial milestones scheduled for completion in fourth quarter of 2014. The Investigational New Drug (IND) application for ProMetic's intravenous immunoglobulin (IVIG) was filed in December 2014 with the American Food and Drug Administration (FDA) and patients' enrolment is expected to commence during this quarter. The enrolment of patients for the Plasminogen Phase 1 clinical trial is progressing as expected. No serious adverse events were reported in the initial part of the PBI-4050 phase 1b/II trial in patients with Diabetic Kidney Disease (DKD). Finally, the completion of the previously announced license and strategic agreement with Generium on December 21, 2014 as well as the achievement of a development milestone in late December 2014 alone contributed approximately $9 Million to fourth quarter of 2014.

ProMetic Life Sciences Inc. and GENERIUM Pharmaceuticals Sign Agreement for Plasma-Derived Biopharmaceuticals

ProMetic Life Sciences Inc. has entered into definitive agreement with GENERIUM Pharmaceuticals for plasma-derived biopharmaceuticals to be manufactured and commercialized in Russia and Commonwealth of Independent States, or CIS. GENERIUM and ProMetic create global partnership for the co-development and commercialization of two plasma-derived coagulating factors. The strategic alliance includes the granting of manufacturing rights by ProMetic to GENERIUM for several plasma-derived biopharmaceuticals using ProMetic's proprietary PPPS technology. In addition, ProMetic will provide training and technical support to manufacture said plasma-derived biopharmaceuticals in a facility to be built and operated by GENERIUM, in Russia. The design of the GENERIUM plasma purification facility will be based on ProMetic's own Laval facility and will have a plasma processing capacity of upto 600,000 litres per year. Construction of facility has already commenced and is expected to be completed by 2017. GENERIUM will fully fund the construction and operating costs of its new cGMP PPPS facility. Once GENERIUM's plasma purification facility becomes operational, both GENERIUM's and ProMetic's facilities may complement each other as contract manufacturing organizations on specific biopharmaceutical products. ProMetic will also supply the required affinity resins for the PPPS based Russian facility and mid-single digit royalties will be paid by GENERIUM to ProMetic on sales of the biopharmaceutical products in the Russian /CIS markets. The strategic alliance also includes two coagulation factors that will be co-developed and commercialized globally with both parties equally sharing net profits from sales.

ProMetic Life Partners with International Biotechnology Center Generium

ProMetic Life Sciences Inc. entered into definitive agreements with International Biotechnology Center Generium (Generium) for several plasma-derived biopharmaceuticals to be manufactured and commercialized in Russia and commonwealth of independent states (CIS), as well as for the co-development and global commercialization of two plasma-derived coagulating factors. Of the $17 million license and milestone fees to be paid by GENERIUM, $6 million is to be paid up front, followed by $11 million of staged payments to ProMetic in relation to defined development milestones. Approximately $4 million of these milestone payments are expected to be received in 2015. In addition, GENERIUM will be funding and conducting clinical trials in Russia /CIS for the plasma-derived biopharmaceuticals providing ProMetic with exclusive rights to valuable, usable clinical data on several products outside of Russia/CIS.


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