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Last $3.95 USD
Change Today +0.04 / 1.02%
Volume 1.2M
As of 8:10 PM 07/30/15 All times are local (Market data is delayed by at least 15 minutes).

orexigen therapeutics inc (OREX) Snapshot

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52 Week High
03/3/15 - $9.37
52 Week Low
10/13/14 - $3.11
Market Cap
Average Volume 10 Days
Shares Outstanding
Dividend Yield

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orexigen therapeutics inc (OREX) Details

Orexigen Therapeutics, Inc., a biopharmaceutical company, focuses on the development of pharmaceutical products in the United States. The company offers Contrave for the treatment of obesity. It has a collaboration agreement with Takeda Pharmaceutical Company Limited to develop and commercialize Contrave in Canada and Mexico. Orexigen Therapeutics, Inc. was founded in 2002 and is headquartered in La Jolla, California.

47 Employees
Last Reported Date: 02/27/15
Founded in 2002

orexigen therapeutics inc (OREX) Top Compensated Officers

Chief Executive Officer, President and Direct...
Total Annual Compensation: $640.6K
Chief Business & Financial Officer and Treasu...
Total Annual Compensation: $379.3K
Head of Global Development and Executive Vice...
Total Annual Compensation: $379.3K
Compensation as of Fiscal Year 2014.

orexigen therapeutics inc (OREX) Key Developments

Orexigen Therapeutics, Inc. Announces Executive Changes

On June 2, 2015, Heather D. Turner gave notice of her resignation as Senior Vice President, General Counsel and Secretary of Orexigen Therapeutics, Inc. Ms. Turner is relocating to the San Francisco Bay Area with her family. Chris Hazuka, Associate General Counsel, will assume the role of acting-General Counsel while the ongoing search for a replacement is completed. The company expects the resignation to be effective on or about June 25, 2015.

Orexigen Therapeutics Announces Early Termination of Contrave Trial

Orexigen Therapeutics announced the early termination of the Light Study, a cardiovascular (CV) outcomes trial that compared its obesity drug Contrave to placebo, in addition to diet and exercise counseling, in 8,909 overweight and obese patients with certain CV risk factors. The study was terminated as an executive steering committee decided the company compromised the trial by prematurely releasing interim data two months ago. Orexigen countered that since continuation of the Light Study was not a post marketing requirement (PMR), and the majority of patients are no longer on blinded study drug, it had long advocated shutting down the study in December 2014, corresponding with the time of the 50% interim analysis, and focusing resources on new studies to further evaluate the therapeutic profile of Contrave. There have been a lot of challenges surrounding the use of interim data from ongoing studies for regulatory purposes. There are competing tensions for data confidentiality to preserve study integrity, transparency laws, and guidelines from regulatory bodies. With respect to the Light Study, Orexigen filed patent applications based on the unexpected result of the 25% interim analysis of LIGHT Study data.

Orexigen Therapeutics, Inc. Presents at Bank of America Merrill Lynch 2015 Health Care Conference, May-12-2015 01:00 PM

Orexigen Therapeutics, Inc. Presents at Bank of America Merrill Lynch 2015 Health Care Conference, May-12-2015 01:00 PM. Venue: Encore at the Wynn, 3131 S Las Vegas Blvd, Las Vegas, Nevada, United States. Speakers: Michael A. Narachi, Chief Executive Officer, President and Director.


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