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Last kr51.25 SEK
Change Today -0.75 / -1.44%
Volume 35.8K
NVP On Other Exchanges
As of 11:30 AM 05/6/15 All times are local (Market data is delayed by at least 15 minutes).

neurovive pharmaceutical (NVP) Snapshot

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52 Week High
08/5/14 - kr82.00
52 Week Low
05/7/14 - kr22.00
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neurovive pharmaceutical (NVP) Details

NeuroVive Pharmaceutical AB (publ) engages in the research and development of mitochondrial-protecting pharmaceuticals in Sweden and Hong Kong. Its product portfolio includes CicloMulsion, a drug candidate, which is in Phase III clinical study for cell protection against reperfusion injury during heart attack treatment; NeuroSTAT, a drug candidate that is in Phase IIa clinical study for the treatment of traumatic brain injuries; and NVP019, an intravenous formulation that is in pre-clinical phase for treating myocardial infarct and traumatic brain injury. The company is also developing NVP014 for brain cell protection in stroke; NVP015 for treating mitochondrial diseases in children and drug-induced mitochondrial dysfunction; and NVP018, an antiviral pharmaceutical product to treat hepatitis B and C. It has collaboration agreements with Isomerase Therapeutics and Sihuan Pharmaceutical; and development and commercialization outlicensing agreement with OnCore BioPharma, as well as agreements with Fresenius Kabi and Lyon University Hospital. The company was founded in 2000 and is headquartered in Lund, Sweden.

Founded in 2000

neurovive pharmaceutical (NVP) Top Compensated Officers

Chief Executive Officer
Total Annual Compensation: kr2.0M
Compensation as of Fiscal Year 2014.

neurovive pharmaceutical (NVP) Key Developments

Neurovive Pharmaceutical AB Announces Clinical Phase II Study for Kidney Protection During Heart Surgery

NeuroVive Pharmaceutical AB announced that the first patient has been enrolled in a clinical phase II study for acute kidney injury using the company’s product CicloMulsion. The study, known as CiPRICS, is being conducted by Skåne University Hospital and will evaluate the product’s ability to prevent acute kidney injury during heart surgery. The CiPRICS (Ciclosporin to Protect Renal function In Cardiac Surgery) study is a double-blind, randomized and placebo-controlled clinical phase II study. The study will include a total of 150 patients at the department of Cardiothoracic Surgery at Skåne University Hospital in Lund, which also initiated the study. Patients will be treated with CicloMulsion® or placebo prior to coronary bypass surgery. The aim is to evaluate whether pre-treatment with a mitochondria-protecting drug protects the kidneys against injury and prevents the compromised renal function that can result from altered blood supply during cardiac surgery. In addition to the patients’ renal function, which will be closely monitored, other markers, such as markers for cardiac injury, will be analyzed.

NeuroVive Pharmaceutical AB Announces Clinical Phase II Study with NeuroSTAT for Traumatic Brain Injury Passes Safety Evaluation

NeuroVive Pharmaceutical AB announced that the independent safety committee has endorsed moving on to the next dose level without any safety issues, following the treatment of 10 of 20 patients in the ongoing clinical Phase IIa study for traumatic brain injury with the company's drug candidate NeuroSTAT. Consequently, the study will continue as planned and move on to the next dosage group. The ongoing CHIC study (Copenhagen Head Injury Ciclosporin Study) is an open-label, non-comparative clinical Phase IIa study enrolling a total of 20 patients divided into two different dosage groups, where NeuroVive's drug candidate NeuroSTAT is being evaluated for the treatment of patients with traumatic brain injury. The study is being conducted at the Department of Neurosurgery at Rigshospitalet, University of Copenhagen, with MD. Jesper Kelsen as Principal Investigator. The study's first dosage group of 10 patients has now been treated with NeuroSTAT at the lower dose, and an interim analysis has been completed by an independent safety committee in order to evaluate the treatment's safety profile. The analysis includes an evaluation of blood concentrations of cyclosporin A (the active substance in NeuroSTAT) and changes in intracranial pressure and blood samples collected to analyze possible organ injury. The low-dose treatment is judged to be safe and the study will now continue as planned with the higher dosage group including 10 additional patients.

NeuroVive Pharmaceutical AB Establishes Subsidiary in Lyon

NeuroVive Pharmaceutical AB has established a subsidiary in Lyon, France. The establishment is part of a process of extending its ongoing collaboration with Hospices Civils de Lyon (HCL) and Professor Michel Ovize (the OPeRa program) to include drug development for the treatment of stroke. The creation of a legal entity in France also coincides with preparations for the potential commercialization of the company’s product CicloMulsion®. The establishment of a French subsidiary, NeuroVive France, increases NeuroVive’s presence in the country while simultaneously extending the partnership with HCL to include drug development for the treatment of stroke. The establishment of a French subsidiary enables NeuroVive to participate as an industrial partner in applications for national funding in France (RHU grants). An application for close to EUR 10 m in funding during a five-year period which includes NeuroVive alongside HCL and other industrial partners has already been submitted.


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