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Last $11.59 USD
Change Today -0.05 / -0.43%
Volume 829.3K
LXRX On Other Exchanges
LXRX is not on other exchanges.
As of 8:10 PM 10/9/15 All times are local (Market data is delayed by at least 15 minutes).

lexicon pharmaceuticals inc (LXRX) Snapshot

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Day High
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52 Week High
09/17/15 - $15.79
52 Week Low
12/15/14 - $5.60
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Average Volume 10 Days
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lexicon pharmaceuticals inc (LXRX) Details

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery and development of pharmaceutical products for the treatment of human diseases. Its drug development programs include telotristat etiprate, an orally-delivered small molecule drug candidate, which is in Phase III clinical trials for the treatment of carcinoid syndrome. The company’s drug development programs also comprise Sotagliflozin, an orally-delivered small molecule drug candidate that has completed Phase II clinical trials to treat type 1 diabetes; and has completed two Phase II clinical trials to treat type 2 diabetes, as well as for the treatment of type 2 diabetes in patients with renal impairment. In addition, it develops LX1033, an orally-delivered small molecule compound, which has completed Phase II clinical trials for the treatment of irritable bowel syndrome; LX2931, an orally-delivered small molecule compound that has completed Phase II clinical trials to treat autoimmune disease; and LX7101, a topically-delivered small molecule compound that has completed Phase I clinical trials for the treatment of glaucoma. Further, the company’s preclinical development programs comprise LX2761, an orally-delivered small molecule compound for the treatment of diabetes. It has license and collaboration agreement with Ipsen Pharma SAS; and drug discovery alliance with Bristol-Myers Squibb Company and Genentech, Inc. The company was founded in 1995 and is headquartered in The Woodlands, Texas.

106 Employees
Last Reported Date: 03/12/15
Founded in 1995

lexicon pharmaceuticals inc (LXRX) Top Compensated Officers

Chief Executive Officer, President and Direct...
Total Annual Compensation: $431.9K
Chief Financial Officer and Executive Vice Pr...
Total Annual Compensation: $534.5K
Executive Vice President of CMC and Supply Op...
Total Annual Compensation: $457.0K
Chief Medical Officer and Executive Vice Pres...
Total Annual Compensation: $445.4K
Compensation as of Fiscal Year 2014.

lexicon pharmaceuticals inc (LXRX) Key Developments

Lexicon Pharmaceuticals, Inc. - Special Call

To discuss complete results of the pivotal Phase 3 TELESTAR study of oral telotristat etiprate in cancer patients with carcinoid syndrome that are not adequately controlled by the current standard of care

Lexicon Pharmaceuticals, Inc. Announces Sotagliflozin Data to be Presented at European Association

Lexicon Pharmaceuticals, Inc. announced that data from its Phase 2 clinical study of sotagliflozin in type 1 diabetes will be presented in oral and poster presentations at the European Association for the study of Diabetes, which will be held September 14 to 18 in Stockholm, Sweden. Currently in Phase 3 clinical development for the treatment of type 1 diabetes, sotagliflozin is the first investigational therapy to target both SGLT1 and SGLT2, key proteins that transport glucose in the body. The oral presentation, entitled Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, improves glycaemic control in type 1 diabetes mellitus in a randomized, placebo-controlled, double-blind study. The poster, entitled Sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, reduces glucose variability in type 1 diabetes mellitus in a randomized, placebo-controlled, double-blind study will be presented at 2:15 p.m., September 17.

Lexicon Pharmaceuticals, Inc. Announces Positive Results from Phase III Carcinoid Syndrome Study

Ipsen SA has announced that Lexicon Pharmaceuticals, Inc. has announced positive results from the Phase III TELESTAR study designed to evaluate the efficacy and safety of telotristat etiprate for carcinoid syndrome patients with metastatic neuroendocrine tumor, or NET, inadequately controlled by somatostatin analog, or SSAs. Top-line results from the Phase III study show that patients who added telotristat etiprate to the standard of care at both the 250 mg and 500 mg doses experienced a statistically significant reduction from baseline compared to placebo in the average number of daily bowel movements over the 12-week study period (p<0.001), meeting the study's primary endpoint. Claude Bertrand, Executive vice president R&D and Chief Scientific Officer, Ipsen stated: "We are pleased with the positive top-line Phase III results for telotristat etiprate. Should telotristat etiprate be approved, its oral formulation would satisfy an unmet medical need for patients with carcinoid syndrome not adequately controlled with SSAs therapy.


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