Last $2.93 USD
Change Today -0.06 / -2.01%
Volume 10.9K
LPTN On Other Exchanges
As of 8:10 PM 02/27/15 All times are local (Market data is delayed by at least 15 minutes).

lpath inc-class a (LPTN) Snapshot

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03/18/14 - $5.17
52 Week Low
12/3/14 - $2.30
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lpath inc-class a (LPTN) Details

Lpath, Inc., a biotechnology company, focuses on the discovery and development of lipidomic-based therapeutic antibodies for treating a range of human diseases primarily in the United States. The company’s lead product candidate includes iSONEP, a monoclonal antibody against sphingosine-1-phosphate (S1P), which has completed Phase I clinical trials to treat wet age-related macular degeneration; and is in Phase 1b/2a clinical trials to treat retinal pigment epithelium detachment. Its products under development also comprise ASONEP, a systemic formulation of sonepcizumab and a mAb against the bioactive lipid S1P that is in Phase 2a clinical trials for the treatment for renal cell carcinoma; various forms of cancer; and other angiogenic-related and inflammatory-oriented indications. In addition, the company is developing Lpathomab, a mAb against lysophosphatidic acid, which is in pre-clinical trials intended for the treatment of neuropathic pain, traumatic brain injury, spinal cord injury, and fibrosis cancer. It has a collaboration agreement with Pfizer Inc. to develop and commercialize iSONEP. Lpath, Inc. is based in San Diego, California.

24 Employees
Last Reported Date: 03/18/14

lpath inc-class a (LPTN) Top Compensated Officers

Chief Financial Officer, Principal Accounting...
Total Annual Compensation: $365.3K
Chief Development Officer and Senior Vice Pre...
Total Annual Compensation: $215.4K
Senior Vice President of Research
Total Annual Compensation: $215.4K
Compensation as of Fiscal Year 2013.

lpath inc-class a (LPTN) Key Developments

Lpath Inc. Submits Investigational New Drug Application for Lpathomab for Neuropathic Pain

Lpath Inc. announced that it has submitted an Investigational New Drug (IND) application to the United States Food and Drug Administration (FDA) to conduct a Phase 1 study of Lpathomab™ for the treatment of neuropathic pain. The primary objective of the study is to evaluate the safety and tolerability of Lpathomab in subjects that are experiencing neuropathic pain. Lpath plans to begin enrolling patients once the FDA's IND review period is complete and the study has been approved by the trial sites' investigational review boards. Lpathomab is an internally discovered, first-in-class antibody targeting Lysophosphatidic Acid, or LPA, a bioactive lipid that has been characterized in the scientific literature as playing a key role in nerve injury and neuropathic pain. Lpath's preclinical studies showed strong in vivo results with Lpathomab in several different pain models, which suggest that LPA may be an attractive target across a variety of chronic pain conditions, including diabetic peripheral neuropathy, post-herpetic neuralgia, chemotherapy-induced neuropathic pain and pain associated with lumbosacral radiculopathy.

Lpath Inc. - Special Call

To update on the progress of the Nexus trial as well as other programs

Lpath Announces Executive Changes

Lpath Inc. announced that Scott Pancoast has resigned as president, chief executive officer and a member of the board of directors, effective from November 3, 2014. The board of directors has appointed biotechnology consultant Michael Lack as the company's interim chief executive officer while the board conducts a search for a new CEO. Mr. Pancoast served as the president and CEO of Lpath since March 2005 and as a director of Lpath since 1998. Mr. Lack currently serves as a member of the board of directors of Immunomic Therapeutics Inc.


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Price/Sales 7.5x
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