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Last $34.06 USD
Change Today -1.52 / -4.27%
Volume 44.2K
As of 10:18 AM 09/1/15 All times are local (Market data is delayed by at least 15 minutes).

la jolla pharmaceutical co (LJPC) Snapshot

Open
$33.83
Previous Close
$35.58
Day High
$35.04
Day Low
$33.83
52 Week High
08/31/15 - $36.60
52 Week Low
10/13/14 - $7.20
Market Cap
519.5M
Average Volume 10 Days
251.4K
EPS TTM
$-2.22
Shares Outstanding
15.3M
EX-Date
--
P/E TM
--
Dividend
--
Dividend Yield
--
Current Stock Chart for LA JOLLA PHARMACEUTICAL CO (LJPC)

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la jolla pharmaceutical co (LJPC) Details

La Jolla Pharmaceutical Company, a biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutics for life-threatening diseases. The company engages in developing LJPC-501, an angiotensin II for the potential treatment of catecholamine-resistant hypotension and hepatorenal syndrome; and GCS-100, a galectin-3 inhibitor for the potential treatment of chronic kidney disease. It also develops LJPC-1010 galectin-3 inhibitor for the potential treatment of nonalcoholic steatohepatitis and other diseases characterized by tissue fibrosis; and LJPC-401, a hepcidin for the potential treatment of hemochromatosis and beta thalassemia. La Jolla Pharmaceutical Company was founded in 1989 and is headquartered in San Diego, California.

25 Employees
Last Reported Date: 03/16/15
Founded in 1989

la jolla pharmaceutical co (LJPC) Top Compensated Officers

Chief Executive Officer, President, Secretary...
Total Annual Compensation: $470.0K
Compensation as of Fiscal Year 2014.

la jolla pharmaceutical co (LJPC) Key Developments

La Jolla Pharmaceutical Company Receives Orphan Drug Designation for Two Novel Compounds for Fibrodysplasia Ossificans Progressiva

La Jolla Pharmaceutical Company announced that the U.S. Food and Drug Administration(FDA) Office of Orphan Products Development has granted La Jolla orphan drug designation for two novel compounds for fibrodysplasia ossificans progressiva (FOP). The compounds that received orphan drug designation are small-molecule kinase inhibitors designed to selectively block a specific member of the bone morphogenetic protein (BMP) type-I receptor family, ALK2. FOP is a rare genetic disorder where the body turns muscle into bone. FOP is caused by a genetic mutation in ALK2 that results in excessive signaling of this pathway. In early childhood, afflicted individuals develop soft tissue swellings that transform into bone. Development of such lesions is exacerbated by trauma, and surgical intervention leads to dramatic and explosive new bone growth.

La Jolla Pharmaceutical Company Announces Exclusive Research and License Agreement Covering Vanderbilt's Research Program and Intellectual Property Rights

La Jolla Pharmaceutical Company announced an exclusive, worldwide research and license agreement covering Vanderbilt's research program and intellectual property rights relating to small-molecule kinase inhibitors designed to selectively block specific members of the bone morphogenetic protein (BMP) type-I receptor family. The seven members of the BMP type-I receptor family, activin receptor-like kinase (ALK) 1-7, play critical roles in human development and physiology. In turn, the improper activation of these receptor pathways is responsible for a wide range of disease conditions. For example, fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder where the body turns muscle into bone, is caused by a genetic mutation in ALK2 that results in excessive signaling of this pathway. Members of the BMP type-I receptor family also are involved in other diseases such as acquired heterotopic ossification (formation of bone in soft tissue caused by injury or trauma), muscular dystrophies including Duchenne muscular dystrophy, anemia of chronic disease (decrease of red blood cells or hemoglobin from chronic infection, chronic immune activation and malignancy), cancer, cardiovascular diseases and inflammatory bowel disease.

La Jolla Pharmaceutical Company Announces FDA Acceptance of IND for LJPC-401

La Jolla Pharmaceutical announced that the U.S. Food and Drug Administration (FDA) has accepted the company’s investigational new drug application (IND) for LJPC-401, La Jolla’s novel formulation of hepcidin. La Jolla expects to release preliminary results from a Phase 1 clinical trial of LJPC-401 by the end of 2015. Hepcidin is a naturally occurring regulator of iron absorption and distribution. By regulating the absorption and distribution of iron, hepcidin prevents excessive iron accumulation in tissues, such as the liver and heart, where it can cause significant damage and even result in death. La Jolla is developing LJPC-401 for the treatment of iron overload, which occurs as a result of diseases such as hereditary hemochromatosis (HH) and beta thalassemia. HH is a disease caused by a genetic deficiency in hepcidin that results in excessive iron accumulation. HH is the most common genetic disease in Caucasians and causes liver cirrhosis, liver cancer, heart disease and/or failure, dementia and diabetes. LJPC-401 has been shown to be effective in reducing serum iron in preclinical testing. Specifically, La Jolla has completed animal toxicology studies that demonstrated a dose-dependent reduction in serum iron levels in all species tested.

 

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LJPC Competitors

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LJPC

Industry Average

Valuation LJPC Industry Range
Price/Earnings NM Not Meaningful
Price/Sales -- Not Meaningful
Price/Book 16.9x
Price/Cash Flow NM Not Meaningful
TEV/Sales -- Not Meaningful
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