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Last $0.25 USD
Change Today -0.009 / -3.46%
Volume 564.8K
HEB On Other Exchanges
As of 11:47 AM 05/5/15 All times are local (Market data is delayed by at least 15 minutes).

hemispherx biopharma inc (HEB) Snapshot

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10/13/14 - $0.40
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hemispherx biopharma inc (HEB) Details

Hemispherx Biopharma, Inc., a specialty pharmaceutical company, engages in the clinical development of new drug therapies based on natural immune system enhancing technologies for the treatment of viral and immune based chronic disorders in the United States. The company’s primary products comprise Ampligen, an experimental drug, which is under clinical development for the treatment of chronic fatigue syndrome, Hepatitis B, HIV, renal cell carcinoma, and malignant melanoma; and Alferon N Injection, an injectable formulation of natural alpha interferon for the treatment of certain categories of genital warts. It is also developing Alferon LDO, a low-dose oral liquid formulation of natural alpha interferon for the treatment of pandemic influenza, seasonal influenza, and other emerging viruses. The company has a strategic alliance with Bioclones (Pty) Ltd. to develop various projects. Hemispherx Biopharma, Inc. was founded in 1990 and is headquartered in Philadelphia, Pennsylvania.

37 Employees
Last Reported Date: 03/19/15
Founded in 1990

hemispherx biopharma inc (HEB) Top Compensated Officers

Chairman, Chief Executive Officer, President,...
Total Annual Compensation: $1.9M
Executive Vice Chairman, Chief Financial Offi...
Total Annual Compensation: $1.3M
Chief Medical Officer and Medical Director
Total Annual Compensation: $336.8K
Compensation as of Fiscal Year 2014.

hemispherx biopharma inc (HEB) Key Developments

Hemispherx Biopharma, Inc. Announces Earnings Results for the Year Ended December 31, 2014

Hemispherx Biopharma, Inc. announced earnings results for the year ended December 31, 2014. For the year, the company reported total revenues were $197,000 compared to $150,000 for the year ended December 31, 2013. Operating loss was $19.1 million compared to operating loss of $17.17 million for the year ended December 31, 2013. Interest and other income was $665,000 compared to $791,000 for the year ended December 31, 2013.

Hemispherx Biopharma to Present Data on the Activity of Ampligen(R) Against the Ebola Virus

Hemispherx Biopharma, Inc. will present integrated findings of new studies of Ampligen (rintatolimod), an experimental therapeutic, performed in various models of Ebola virus infection. The findings will be presented during the 7th International Symposium on Filoviruses - Ebola: West Africa and Recent Developments in Washington, DC, March 25-28, 2015. The conference brings together international experts to deal with various aspects of controlling the ongoing Ebola outbreak in West Africa. Hemispherx's commitment regarding research related to pandemic (influenza), and potential pandemic viruses such as SARS, MERS-COV, and Ebola, lies in its belief: these viruses all share a common mechanism of inducing high lethality based on inactivation of innate immunity. Ampligen, an experimental, broad-spectrum antiviral, restores innate immunity in a number of model systems of various pandemic viruses, the scarcity of available experimental therapeutics to test is generally great at the outset of any potential new pandemic which places a high priority on experimental products with a well-developed portfolio of prior animal studies and a known clinical safety profile in other, non-pandemic, disease settings. Double-stranded RNA (dsRNA) is a common component of viral replication and initiates signaling pathways that normally activate innate immune responses, including interferon (IFN) antiviral cascades. Ebola virus disease induces a relative dsRNA deficiency. The IFN induced antiviral pathways include expression of two enzymes, 2'-5' adenylate synthetase and protein kinase R, which require dsRNA as a co-factor for activation. Rintatolimod (PolyI:PolyC12U), Ampligen, an experimental therapeutic, was designed to induce IFN, but with a reduced incidence of adverse events (AEs) compared to polyI:polyC, and has demonstrated broad antiviral activity against both DNA and RNA viruses. The hypothesized mechanism of action against EBOV is that VP35 binding of viral dsRNA creates a relative dsRNA deficiency and blocks IFN induction which Ampligen, a synthetic dsRNA, reverses. Recent results encouraged Hemispherx to move forward its experimental therapeutic Ampligen in the fight against this dread disease presently plaguing West Africa and to continue to work with various international organizations committed to the effort to mitigate the ongoing morbidity and mortality of Ebola. Recently, one of the two experimental therapeutics in active evaluation in West Africa was withdrawn from clinical studies leaving the experimental product, favipiravir, as a principal antiviral agent for active clinical trials. Ampligen also exhibits broad-spectrum antiviral activity against other viruses that are highly pathogenic to humans, including the SARS virus (Day, et al. Virology 2009;395:210-222) and Western Equine Encephalitis Virus (WEEV), where Ampligen demonstrated a greater than 2 fold survival benefit (mice) compared to favipiravir, a potential Ebola treatment (Julander, et al. Antiviral Res 2009;82(3):169-171).

Hemispherx Biopharma, Inc. Announces Earnings Results for the Year Ended December 31, 2014

Hemispherx Biopharma, Inc. announced earnings results for the year ended December 31, 2014. The net loss (including non-cash effects) was approximately $17,450,000 or $0.09 per share as compared to a net loss of $16,225,000 or $0.10 per share for the same twelve month period in 2013.


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Price/Book 2.1x
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TEV/Sales 200.8x

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