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Last $7.12 USD
Change Today -0.05 / -0.70%
Volume 63.6K
FATE On Other Exchanges
As of 8:10 PM 07/29/15 All times are local (Market data is delayed by at least 15 minutes).

fate therapeutics inc (FATE) Snapshot

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05/6/15 - $8.78
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12/12/14 - $3.50
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fate therapeutics inc (FATE) Details

Fate Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops programmed cellular therapeutics for the treatment of severe, life-threatening diseases. It has a platform to program the function and fate of cells ex vivo using pharmacologic modulators, such as small molecules. The company focuses primarily on developing programmed hematopoietic cellular candidates as therapeutic entities for the treatment of hematologic malignancies, rare genetic disorders, and diseases resulting from the dysregulation of the immune system. The company’s lead product candidate is ProHema, an ex vivo programmed hematopoietic cellular therapeutic derived from umbilical cord blood that is in Phase II clinical development for hematologic malignancies in adults; in Phase Ib clinical development for hematologic malignancies in pediatric patients; and in Phase Ib clinical development for inherited metabolic disorders in pediatric patients. It is also developing a triple modulator combination of pharmacologic modulators that programs human CD34+ cells to express high levels of PD-L1, a key immunosuppressive protein; and in vivo therapeutic potential of PD-L1 programmed CD34+ cells to selectively home to sites of, and suppress, T cell proliferation, and cytokine production. Fate Therapeutics, Inc. was founded in 2007 and is headquartered in San Diego, California.

50 Employees
Last Reported Date: 03/12/15
Founded in 2007

fate therapeutics inc (FATE) Top Compensated Officers

Chief Executive Officer, President and Direct...
Total Annual Compensation: $350.0K
Chief Operating Officer and Chief Financial O...
Total Annual Compensation: $310.0K
Compensation as of Fiscal Year 2014.

fate therapeutics inc (FATE) Key Developments

Fate Therapeutics Enters into Research Collaboration with University of Minnesota on Development of Natural Killer Cell-Based Immuno-Oncology Candidates

Fate Therapeutics entered into a research collaboration with the University of Minnesota focused on the development of natural killer (NK) cell-based immuno-oncology candidates. Fate Therapeutics will leverage the University's pioneering work on NK cell-based therapies, as well as its own cell-programming and stem-cell technology platform to develop 'off-the-shelf' candidates with anti-tumour activity. The collaboration will focus on two main therapeutic projects, one related to optimisation of 'adaptive' NK cells, and the other focused on utilisation of induced pluripotent stem cells (iPSCs) to derive NK cell-based candidates. Based on the terms of the agreement, Fate Therapeutics has the option to obtain exclusive patent rights to candidates resulting from the collaboration.

Fate Therapeutics, Inc. Appoints Dr. Stewart Abbot as Vice President, Translational Research

Fate Therapeutics, Inc. announced that it has named Dr. Stewart Abbot as Vice President, Translational Research, effective immediately. Dr. Abbot comes to Fate Therapeutics from Celgene Corporation, where he most recently served as Executive Director, Integrative Research at Celgene Cellular Therapeutics. In his role at Fate Therapeutics, Dr. Abbot will be responsible for charting the advancement of the company's innovative pipeline of programmed cellular immunotherapeutics from discovery into early clinical development.

Fate Therapeutics, Inc. Signs Research Agreement with Boston Children's Hospital

Fate Therapeutics, Inc. has signed a two-year sponsored research agreement with Boston Children's Hospital to develop an adoptive immunoregulatory cell therapy to treat autoimmune diseases. The collaboration seeks to assess the potential of Fate's PD-L1 programmed CD34+ cellular therapeutic as a transformative treatment for type 1 diabetes. The company's adoptive immunoregulatory cell therapy is currently undergoing preclinical testing across a range of autoimmune and inflammatory diseases. The research program will be led by Paolo Fiorina, M.D., Ph.D., Assistant Professor of Pediatrics at Boston Children's Hospital and Harvard Medical School. Under the agreement, Dr. Fiorina will investigate the potential of Fate's PD-L1 programmed CD34+ cellular therapeutic to abrogate autoimmune activity responsible for the destruction of pancreatic beta cells and the development of type 1 diabetes. Preclinical data from the Fiorina laboratory shows that genetically engineered PD-L1+ hematopoietic cells adoptively transferred into hyperglycemic mice traffic to the pancreas, reduce aberrant T cell activity and revert hyperglycemia in a well-established murine model of type 1 diabetes.


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