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Last 398.00
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EXEN On Other Exchanges
Tel Aviv
As of 10:24 AM 07/29/15 All times are local (Market data is delayed by at least 15 minutes).

exalenz bioscience ltd (EXEN) Snapshot

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exalenz bioscience ltd (EXEN) Details

Exalenz Bioscience Ltd. develops and commercializes tools for the diagnosis and management of a range of conditions in the fields of liver health and gastroenterology. It offers BreathID Hp, a urea breath test for diagnosing helicobacter pylori infection; and for post-treatment monitoring of helicobacter pylori infection in adults in the areas of primary care, gastric distress, bariatric surgery, and emergency room and urgent care facilities. The company serves hepatologists, gastroenterologists, bariatric surgeons, urgent care centers, and primary care physicians in Israel and internationally. Exalenz Bioscience Ltd. is based in Modiin, Israel.

exalenz bioscience ltd (EXEN) Top Compensated Officers

Chief Executive Officer
Total Annual Compensation: 1.1M
Chief Financial Officer
Total Annual Compensation: 573.0K
Chief Operating Officer and General Manager
Total Annual Compensation: 658.0K
Vice President of Marketing and Business Deve...
Total Annual Compensation: 564.0K
Vice President of Sales
Total Annual Compensation: 703.0K
Compensation as of Fiscal Year 2014.

exalenz bioscience ltd (EXEN) Key Developments

Exalenz Bioscience Ltd Launches Clinical Study for Breath-Based Detection of Primary Liver Cancer (HCC)

Exalenz Bioscience announced the initiation of a clinical study designed to investigate its BreathID® test to non-invasively detect primary liver cancer, also known as Hepatocellular Carcinoma (HCC). The 100 patient study, being conducted initially at the 302 Military Hospital of China, with other sites in China expected to be added, will evaluate the efficacy of BreathID for the early detection of HCC, compared to magnetic resonance imaging (MRI). MRI is currently part of the recommended practice guidelines by leading medical organizations including the European Association for the Study of the Liver (EASL) and the American Association for the Study of Liver Diseases (AASLD). Following completion of the study, Exalenz plans to conduct a Pivotal study and submit data to both the U.S. Food and Drug Administration (FDA) and the Chinese Food and Drug Administration (CFDA) in support of marketing approval. The efficacy of the Exalenz breath test for detection of HCC was evaluated in a prior clinical study demonstrating a very high correlation with imaging tests like computed tomography that are currently the standard of care. The company estimates the market value of this test is approximately $380 million in China alone. This study is part of Exalenz's growing clinical pipeline of investigational diagnostic applications for serious liver diseases. In May, the Company announced the initiation of a clinical study evaluating the potential of its BreathID® test to diagnose nonalcoholic steatohepatitis (NASH). Exalenz also has an ongoing pivotal study, launched October 2014, investigating BreathID® as a tool to diagnose Clinically Significant Portal Hypertension (CSPH).

Exalenz Bioscience Launches Additional Clinical Study of Breath-Based Diagnostic Test

Exalenz Bioscience announced the initiation of a clinical study evaluating the potential of its BreathID test to diagnose nonalcoholic steatohepatitis. NASH is a progressive liver disease characterized by an accumulation of fat in the liver, inflammation and fibrosis, which can lead to cirrhosis, hepatocellular cancer and liver failure. Currently, a definitive diagnosis of NASH can only be achieved through liver biopsy, which is invasive and introduces potential for sampling errors as well as other interpretation limitations. The 200-patient multicenter prospective study will investigate the clinical utility of BreathID to diagnose NASH compared to liver biopsy, standard pathological examinations and blood testing. Nonalcoholic fatty liver disease is a significant cause of chronic liver disease affecting both children and adults and its incidence continues to rapidly expand in the Western world. Cases of NASH, the most serious form of NAFLD, also are increasing. A major challenge for healthcare system is the lack of accurate, non-invasive tools for diagnosing and monitoring the progression of the disease and the effect of therapies on NASH. The BreathID platform shows promise as a convenient, non-invasive diagnostic technology to assist clinicians in managing patients efficiently and rapidly. The BreathID ideally could determine which patients need to undergo further investigation (e.g. biopsy) and help decide which patients should be treated when therapies become available. The results of this study will be used to optimize the company's proprietary algorithm for diagnosing and monitoring the progression of NASH and the effect of treatment on the disease. It is expected that the optimized algorithm will then be applied to data collected in larger studies in collaboration with pharmaceutical companies investigating treatments for NASH. Exalenz plans to launch additional clinical studies for the diagnosis and monitoring of additional liver indications in the near future, including hepatocellular carcinoma, and to participate in studies for acute liver failure and therapeutic NASH studies. These goals will be achieved in part through partnering with companies developing therapies for these diseases.

Exalenz Bioscience Ltd, Annual General Meeting, Apr 16, 2015

Exalenz Bioscience Ltd, Annual General Meeting, Apr 16, 2015., at 10:00 Israel Standard Time.


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