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epistem holdings plc (EHP) Snapshot

272.50 GBp
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272.50 GBp
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272.50 GBp
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272.50 GBp
52 Week High
06/18/14 - 340.00 GBp
52 Week Low
01/7/15 - 272.50 GBp
Market Cap
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-0.17 GBp
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Dividend Yield
Current Stock Chart for EPISTEM HOLDINGS PLC (EHP)

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epistem holdings plc (EHP) Details

Epistem Holdings Plc, a biotechnology and personalised medicine company, provides pre-clinical testing, pharmacogenomic biomarker, and diagnostic testing services to the biotechnology and pharmaceutical industries in Europe, the United States, and Asia. It operates through three divisions: Preclinical Research Services, Personalised Medicine, and Novel Therapies. The Preclinical Research Services division provides preclinical efficacy testing, immunohistochemistry services, and cell biology expertise in the areas of oncology, oncology supportive care, inflammatory bowel disease, rheumatoid arthritis, and dermatology. The Personalised Medicine division offers sensitive molecular measures of biological processes that enhance precision in drug development and disease treatment. This division discovers, develops, and translates biomarkers for clinical drug development and companion diagnostics; and offers Genedrive, a molecular diagnostic device used in bacterial, viral, fungal, and somatic mutations disease identification. The Novel Therapies division discovers and develops regulators of epithelial stem cells and tissues. Epistem Holdings Plc was founded in 2000 and is headquartered in Manchester, the United Kingdom.

Founded in 2000

epistem holdings plc (EHP) Top Compensated Officers

Chief Executive Officer and Director
Total Annual Compensation: 302.0K GBP
Co-Founder, Managing Director of Contract Res...
Total Annual Compensation: 107.3K GBP
Chief Financial Officer, Finance Director, Co...
Total Annual Compensation: 133.1K GBP
Chief Operating Officer of Diagnostics and Di...
Total Annual Compensation: 62.5K GBP
Compensation as of Fiscal Year 2014.

epistem holdings plc (EHP) Key Developments

EpiStem Holdings Plc, Annual General Meeting, Jan 12, 2015

EpiStem Holdings Plc, Annual General Meeting, Jan 12, 2015., at 09:30 GMT Standard Time. Location: The Incubator Building.

Epistem Holdings plc Appoints Ian Gilham as Non-Executive Director and Chairman

EpiStem Holdings Plc announced that Ian Gilham has joined the Board as a non-executive director and chairman designate with immediate effect. As previously announced, David Evans, the chairman of Epistem since 2006 will be standing down as chairman at the point that the company launches Genedrive® its revolutionary handheld molecular diagnostic device in India, which is expected early in 2015. an David Gilham, aged 54, is currently non-executive chairman of three life sciences companies including AIM quoted Horizon Discovery Group plc, which provides research tools to support translational genomics and the development of personalised medicine, Multiplicom NV focussed on the development and commercialisation of DNA sequencing products and Biosurfit SA, focussed on development and commercialisation of point-of-care diagnostic products.

EpiStem Holdings Plc Announces Successful Completion of Genedrive(R) Indian Clinical Trials and Regulatory Submission

EpiStem Holdings Plc announced the successful completion of its Genedrive(R) Indian clinical evaluation study and the regulatory submission with the Drug Controller General of India (DCGI) of its first test for the diagnosis of Tuberculosis and Rifampicin antibiotic resistance (TB). Epistem is now awaiting approval from the Indian regulator for a license to import and sell its first major infectious disease assay for TB, which is anticipated early in 2015. The clinical evaluation study was completed over a 4-month period ending September 2014 and involved the testing of 300 randomly referred and blinded pulmonary 'raw sputa' TB patient samples, with each Genedrive(R) test taking approximately 1 hour to complete. The test results demonstrated high levels of sensitivity (93%) and specificity (94%), versus the industry gold standard 'culture test' method for TB. The study also measured those patients showing resistance to the first line antibiotic Rifampicin, a growing concern due to irregular and incomplete treatment with differing regimens giving rise to the growth in Multi Drug Resistance-TB (MDR-TB) cases in India. These levels of accuracy, speed to result and simplicity of operation compare favourably with other molecular and non-molecular TB test methods, such as culture which has lengthy turn around times to test result (culture testing typically takes up to 42 days to obtain a confirmed TB test result), microscopy which delivers less accurate results (lower sensitivity and specificity) and other competitive molecular tests which can require lengthy upfront extraction processes, extended timescales to test result and/or increased cost. Genedrive's advantage is its ability to deliver speed to result, high levels of molecular accuracy and simplicity of use at low cost in remote/non laboratory-based settings, making it suitable for tackling disease in low-income countries and developing nations. India is the high TB burden country in the world with World Health Organisation (WHO) statistics for 2011 giving an estimated incidence figure of 2.2 million cases of TB for India out of a global incidence of 8.7 million cases. Indian distributor partner Xcelris Lab is preparing for the launch of TB test including first line antibiotic resistance (Rifampicin) detection.


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