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Last $0.83 USD
Change Today +0.0037 / 0.45%
Volume 227.6K
DSCO On Other Exchanges
Symbol
Exchange
NASDAQ CM
As of 8:10 PM 05/22/15 All times are local (Market data is delayed by at least 15 minutes).

discovery laboratories inc (DSCO) Snapshot

Open
$0.84
Previous Close
$0.83
Day High
$0.85
Day Low
$0.82
52 Week High
07/7/14 - $2.03
52 Week Low
05/19/15 - $0.78
Market Cap
71.5M
Average Volume 10 Days
1.9M
EPS TTM
$-0.51
Shares Outstanding
85.7M
EX-Date
--
P/E TM
--
Dividend
--
Dividend Yield
--
Current Stock Chart for DISCOVERY LABORATORIES INC (DSCO)

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discovery laboratories inc (DSCO) Details

Discovery Laboratories, Inc., a specialty biotechnology company, focuses on developing products for critical-care patients with respiratory disease and improving care in pulmonary medicine. Its proprietary drug technology produces a synthetic peptide-containing surfactant (KL4 surfactant in liquid, lyophilized, and aerosolized dosage forms), as well as develops drug delivery technologies to enable efficient delivery of its aerosolized KL4 surfactant. The company offers SURFAXIN Intratracheal suspension for the prevention of respiratory distress syndrome (RDS) in premature infants; AFECTAIR device, a disposable aerosol-conducting airway connector for infants; and WARMING CRADLE, a dry-block heating device that is designed to warm drug vials at the same temperature that is designated in the SURFAXIN prescribing information. It is also developing AEROSURF, a drug/device combination product that delivers KL4 surfactant in aerosolized form using the lyophilized KL4 surfactant is in Phase II clinical trials for the treatment of RDS in premature infants. In addition, the company is developing a lyophilized (freeze-dried) dosage form of its KL4 surfactant. The company has a collaboration agreement with Battelle Memorial Institute for the development and commercialization of AEROSURF; and a strategic alliance with Laboratorios del Dr. Esteve, S.A. for the development, marketing, and sale of a portfolio of KL4 surfactant products in Andorra, Greece, Italy, Portugal, and Spain. Discovery Laboratories, Inc. was founded in 1992 and is headquartered in Warrington, Pennsylvania.

58 Employees
Last Reported Date: 05/11/15
Founded in 1992

discovery laboratories inc (DSCO) Top Compensated Officers

Chief Executive Officer, President and Direct...
Total Annual Compensation: $400.0K
Chief Financial Officer, Chief Accounting Off...
Total Annual Compensation: $253.5K
Senior Vice President, General Counsel and Co...
Total Annual Compensation: $303.5K
Chief Development Officer and Senior Vice Pre...
Total Annual Compensation: $186.4K
Compensation as of Fiscal Year 2014.

discovery laboratories inc (DSCO) Key Developments

Discovery Labs Announces Enrollment of First Patient in AEROSURF® Phase 2A Dose Expansion Trial

Discovery Laboratories Inc. reported that the first patient has been enrolled in the next phase of its phase 2a clinical evaluation of AEROSURF®, which is designed to evaluate the safety and tolerability of higher and repeat doses of aerosolized KL4 surfactant administered to premature infants 29 to 34 weeks gestational age (GA) who are receiving nasal continuous positive airway pressure (nCPAP) for respiratory distress syndrome (RDS), compared to infants receiving nCPAP alone. This phase is intended to expand upon the knowledge gained in the recently completed phase 2a clinical trial, the results of which were reported in mid-May 2015. The Company expects to complete this study in the fourth quarter of 2015. The recently completed phase 2a clinical trial was designed to assess the safety and tolerability of three escalating single doses of aerosolized KL4 surfactant in premature infants 29 to 34 weeks gestational age who are receiving nCPAP for RDS, compared to infants receiving nCPAP alone. All key objectives were achieved, including the primary objective of demonstrating a favorable safety and tolerability profile of AEROSURF, establishing proof of concept for the Company's proprietary technology platform based on physiological data suggesting that aerosolized KL4 surfactant is being delivered into the lung of premature infants, and acceptable performance of the novel capillary aerosol generator (CAG) technology in the neonatal intensive care unit (NICU). This next phase 2a dose expansion study is a multicenter, randomized, open-label, controlled study and is designed to evaluate the safety and tolerability of aerosolized KL4 surfactant administered in higher and repeat doses in premature infants 29 to 34 weeks GA who are receiving nCPAP for RDS, compared to infants receiving nCPAP alone. In addition to safety and tolerability, another objective of the expansion study is to continue to evaluate the physiological effects of higher and repeat dosing of aerosolized KL4 surfactant. The results of this expansion trial are expected to provide further insight and data to support the design of the planned AEROSURF phase 2b clinical program.

Discovery Laboratories Inc. Reports Top Line Data from AEROSURF® Phase 2A Clinical Trial

Discovery Laboratories Inc. reported top line data from its recently completed AEROSURF® phase 2a clinical trial in premature infants with respiratory distress syndrome. Key objectives of the study were achieved, including (1) the primary objective of demonstrating the safety and tolerability of a single exposure of aerosolized KL4 surfactant administered in three escalating inhaled doses to premature infants 29 to 34 week gestational age and receiving nasal continuous positive airway pressure (nCPAP) for RDS, compared to infants receiving nCPAP alone, and (2) establishing proof of concept for the Company's proprietary technology platform based on physiological data suggesting that aerosolized KL4 surfactant is being delivered into the lung of premature infants, and acceptable performance of the novel capillary aerosol generator (CAG) technology in the neonatal intensive care unit (NICU). AEROSURF is Discovery Labs' combination drug/device product that combines the Company's novel synthetic peptide-containing (KL4) surfactant and its proprietary aerosol delivery technologies, including the CAG, that are designed to enable efficient delivery of aerosolized KL4 surfactant. Currently, the available surfactants (animal-derived) can only be administered using endotracheal intubation with mechanical ventilation, invasive procedures that may each result in serious complications and other respiratory conditions. With AEROSURF, neonatologists potentially will be able to administer aerosolized KL4 surfactant to premature infants supported with nCPAP alone, without having to resort to invasive intubation and mechanical ventilation.

Discovery Laboratories Inc. - Special Call

To discuss results from its AEROSURF Phase 2a clinical trial

 

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