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Last $2.34 USD
Change Today -0.05 / -2.09%
Volume 542.5K
DRRX On Other Exchanges
As of 8:10 PM 07/1/15 All times are local (Market data is delayed by at least 15 minutes).

durect corporation (DRRX) Snapshot

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52 Week High
06/8/15 - $3.42
52 Week Low
10/27/14 - $0.68
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Current Stock Chart for DURECT CORPORATION (DRRX)

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durect corporation (DRRX) Details

DURECT Corporation, a specialty pharmaceutical company, focuses on the development of pharmaceuticals products based on its proprietary drug formulations and delivery platform technologies in the United States, Europe, Japan, and internationally. It provides ALZET product line comprising osmotic pumps and accessories that are used for experimental research in mice, rats, and other laboratory animals; and a range of biodegradable polymers, which are used as raw materials for pharmaceutical and medical device under the LACTEL brand. It also focuses on developing products for various chronic and episodic, or acute medical conditions, including pain, central nervous system disorders, metabolic disorders, cardiovascular disease, ophthalmic disorders, and other diseases. The company develops REMOXY, an oral oxycodone gelatin capsule for chronic pain; POSIDUR, a formulation of bupivacaine for the treatment of post-surgical pain; ELADUR, a transdermal bupivacaine for the treatment of pain associated with post-herpetic neuralgia; and Relday, a risperidone product to treat the symptoms of schizophrenia and bipolar I disorder in adults and teenagers. It also develops ORADUR-ADHD, a drug candidate for the treatment of attention deficit hyperactivity disorder; ORADUR-based opioids, including hydrocodone and hydromorphone that are in Phase I clinical trials to treat chronic pain, and oxymorphone; and DUR-928, an endogenous small molecule for the treatment of acute organ injuries and metabolic/lipid disorders. The company has collaboration agreements with Santen Pharmaceutical Co., Ltd., Impax Laboratories, Inc., Zogenix, Inc., Pain Therapeutics, Inc., and Hospira, Inc. DURECT Corporation was founded in 1998 and is headquartered in Cupertino, California.

103 Employees
Last Reported Date: 05/1/15
Founded in 1998

durect corporation (DRRX) Top Compensated Officers

Co-Founder, Chief Executive Officer, Presiden...
Total Annual Compensation: $470.4K
Co-Founder, Chairman and Chief Scientific Off...
Total Annual Compensation: $277.5K
Chief Financial Officer
Total Annual Compensation: $322.1K
Senior Vice President of Operations and Corpo...
Total Annual Compensation: $275.8K
Executive Vice President of Pharmaceutical Sy...
Total Annual Compensation: $340.0K
Compensation as of Fiscal Year 2014.

durect corporation (DRRX) Key Developments

DURECT Corporation(NasdaqGM:DRRX) added to Russell 2000 Index

DURECT Corporation will be added to Russell 2000 Index

DURECT Corporation(NasdaqGM:DRRX) added to Russell 3000 Index

DURECT Corporation will be added to the Russell 3000 Index.

DURECT Corporation Announces Plans to Conduct A New POSIDUR Phase 3 Clinical Trial

DURECT Corporation announced that, based on feedback from the FDA, it plans to conduct a new POSIDUR Phase 3 clinical trial consisting of approximately 300 patients undergoing laparoscopic cholecystectomy (gallbladder removal) surgery. DURECT anticipates beginning the trial in the fall of 2015 and expects that it will take approximately one year to complete enrollment. The study will be a randomized, parallel-group, double-blind, placebo-controlled, multicenter trial of POSIDUR in patients undergoing laparoscopic cholecystectomy. The objective of the study will be to evaluate the safety and efficacy of POSIDUR for the management of postoperative pain. Approximately 300 patients will be randomized on a one-to-one basis to receive either POSIDUR or placebo as a one-time intra-incisional instillation at the close of surgery. The primary efficacy endpoint will be pain intensity on movement over 0-72 hours after surgery. Cholecystectomy is a surgical procedure for removal of the gallbladder. Laparoscopic cholecystectomy, which is done using a camera and instruments inserted through a set of small incisions in the abdomen, has largely supplanted the traditional open approach, which requires an abdominal incision several inches in length. Approximately 800,000 such procedures are performed in the U.S. each year, most of them on an outpatient basis. In a previous clinical trial consisting of 50 patients, when using the statistical analysis that will be employed in the upcoming trial, POSIDUR demonstrated an approximately 25% reduction in pain intensity on movement for the first 3 days after surgery (p=0.0235) when compared with the active control bupivacaine hydrochloride.


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Price/Sales 15.2x
Price/Book 18.5x
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