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Last $2.39 USD
Change Today +0.07 / 3.02%
Volume 491.7K
CYTR On Other Exchanges
As of 8:10 PM 08/28/15 All times are local (Market data is delayed by at least 15 minutes).

cytrx corp (CYTR) Snapshot

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04/21/15 - $5.42
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08/25/15 - $1.98
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cytrx corp (CYTR) Details

CytRx Corporation operates as a biopharmaceutical research and development company specializing in oncology. The company’s product candidate is aldoxorubicin, which is in Phase III clinical trial as a therapy for patients with soft tissue sarcomas (STS) whose tumors have progressed following treatment with chemotherapy; in Phase IIb clinical trial in small cell lung cancer; in Phase II clinical trial in HIV-related Kaposi's sarcoma; in Phase II clinical trial in patients with late-stage glioblastoma (brain cancer); in Phase Ib trial in combination with ifosfamide in patients with soft tissue sarcoma; and in Phase Ib trial in combination with gemcitabine in subjects with metastatic solid tumors. It also has completed Phase 2b and Phase 1b/2 clinical trials with aldoxorubicin as a first-line therapy for STS; a Phase 1b clinical trial of aldoxorubicin in combination with doxorubicin in patients with advanced solid tumors; and a Phase 1b pharmacokinetics clinical trial in patients with metastatic solid tumors. CytRx Corporation was founded in 1985 and is headquartered in Los Angeles, California.

26 Employees
Last Reported Date: 03/10/15
Founded in 1985

cytrx corp (CYTR) Top Compensated Officers

Chairman, Chief Executive Officer and Preside...
Total Annual Compensation: $1.3M
Chief Financial Officer, Chief Accounting Off...
Total Annual Compensation: $450.0K
Chief Medical Officer and Executive Vice Pres...
Total Annual Compensation: $825.0K
Senior Vice President of Drug Development
Total Annual Compensation: $650.0K
Senior Vice President of Legal Affairs, Gener...
Total Annual Compensation: $450.0K
Compensation as of Fiscal Year 2014.

cytrx corp (CYTR) Key Developments

CytRx Corporation Announces Unaudited Earnings Results for the Second Quarter and Six Months Ended June 30, 2015

CytRx Corporation announced unaudited earnings results for the second quarter and six months ended June 30, 2015. For the quarter, the company reported loss before other income of $14,200,073 compared with $13,337,004 for the same period a year ago. Net loss was $11,687,093 or $0.21 per basic and diluted share compared with $15,719,473 or $0.28 per basic and diluted share for the same period a year ago. The decrease of $4.0 million in net loss during the current three-month period resulted primarily from a gain of $2.4 million on warrant derivative liability in the current quarter, as compared to a loss on warrant derivative liability of $2.5 million in the comparative 2014 period, for a difference of $4.9 million. For the six months, the company reported loss before other income of $29,895,182 compared with $23,455,926 for the same period a year ago. Net loss was $29,211,643 or $0.52 per basic and diluted share compared with $11,054,955 or $0.21 per basic and diluted share for the same period a year ago.

CytRx Seeks Acquisitions

CytRx Corporation (NasdaqCM:CYTR) is seeking acquisitions. The net proceeds of the offering may be used to acquire additional product candidates or complementary assets or businesses.

CytRx Corporation Announces Encouraging Interim Data from Phase II Kaposi's Sarcoma Study

CytRx Corporation announced encouraging interim data from its ongoing open-label Phase II pilot study evaluating the efficacy and safety of aldoxorubicin for the treatment of Kaposi's sarcoma (KS), in HIV-infected patients. For the study, patients with biopsy-confirmed KS were administered 100 or 150 mg/m2 aldoxorubicin (75 or 112 mg/m2 doxorubicin equivalents) IV every three weeks. At the time of presentation, preliminary analyses were available for nine patients who received at least six cycles of drug (mean = 6.3 cycles). Four patients had received prior Doxil chemotherapy. Of these 9 patients, 6 (67%) demonstrated a partial response (PR) to aldoxorubicin at the end of study visit (EOS), and 7 (78%) demonstrated PR within 4 months of EOS. Doxorubicin could be detected in all tumor biopsies and higher doxorubicin concentrations were demonstrated within KS lesions relative to skin next to the lesions for 3/4 (75%) patients for whom adequate tissue was available for analysis. Five of 6 (83%) patients receiving aldoxorubicin and for whom data are available exhibited reduced intratumoral viral loads during therapy. A subset of patients also exhibited improvements in quality of life during treatment, and all patients exhibited either improvement or stability in immunologic and virologic HIV treatment parameters. Aldoxorubicin was well-tolerated, with only 2 patients (22%) experiencing a grade 4 adverse event (transient neutropenia and anemia), and overall AEs (44%) were mild and compared favorably with AE rates from other trials enrolling KS patients representing urban, minority-predominant populations. This open-label Phase II clinical trial is expected to enroll up to 30 patients, randomly assigned to two equally sized treatment arms which will receive aldoxorubicin at 100 or 150 mg/m2 by 30-minute intravenous infusion. Because the KS patients in the study have compromised immune systems, the aldoxorubicin dosages administered in the trial are lower than those administered in the Company's clinical testing of aldoxorubicin in patients with soft tissue sarcomas. Patients with advanced KS receive aldoxorubicin on day 1, then every 3 weeks until evidence of tumor progression, unacceptable toxicity or withdrawal of consent. The primary objectives of preliminary efficacy include evaluation of the size, number and nodularity of skin lesions, change in size and number of lung lesions and changes in the number of tumor cells that express viral DNA (Kaposi sarcoma-associated herpesvirus, the etiologic agent of KS). The company is also evaluating the level of aldoxorubicin uptake into lesions. Safety is being assessed through monitoring of adverse events and the ability to remain on assigned treatment. The trial is being conducted at the Louisiana State University Health Sciences Center in New Orleans, LA.


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