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Last $1.84 USD
Change Today -0.01 / -0.54%
Volume 942.1K
CTIC On Other Exchanges
As of 5:20 PM 08/3/15 All times are local (Market data is delayed by at least 15 minutes).

cti biopharma corp (CTIC) Snapshot

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52 Week High
03/9/15 - $2.94
52 Week Low
05/26/15 - $1.65
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cti biopharma corp (CTIC) Details

CTI BioPharma Corp., a biopharmaceutical company, engages in the acquisition, development, and commercialization of novel targeted therapies for blood-related cancers in the United States and internationally. It primarily focuses on the commercialization of PIXUVRI, an aza-anthracenedione derivative for the treatment of adult patients with multiply relapsed or refractory aggressive B-cell non-Hodgkin lymphoma in the European Union. The company is also developing Pacritinib, an oral multikinase inhibitor with activity against Janus Kinase 2 and FMS-like tyrosine kinase, which is in Phase III clinical trials for the treatment of myelofibrosis. In addition, it is developing Tosedostat, an oral once-daily aminopeptidase inhibitor that is in Phase II/III clinical trials for the treatment of acute myeloid leukemia; and Opaxio, a chemotherapeutic agent, which is in Phase III clinical trials for the treatment of various solid tumors, including non-small cell lung, ovarian, breast, and prostate cancers. The company has development, commercialization, and license agreement with Baxter International Inc., Baxter Healthcare Corporation, and Baxter Healthcare SA for the development and commercialization of pacritinib for use in oncology and other therapeutic areas. The company was formerly known as Cell Therapeutics, Inc. and changed its name to CTI BioPharma Corp. in May 2014. CTI BioPharma Corp. was founded in 1991 and is headquartered in Seattle, Washington.

132 Employees
Last Reported Date: 03/12/15
Founded in 1991

cti biopharma corp (CTIC) Top Compensated Officers

Principal Founder, Chief Executive Officer, P...
Total Annual Compensation: $1.3M
Co-Founder, Principal Financial Officer, Prin...
Total Annual Compensation: $594.0K
Co-Founder, Interim Chief Medical Officer, Ch...
Total Annual Compensation: $545.8K
Executive Vice President of Corporate Develop...
Total Annual Compensation: $544.4K
Compensation as of Fiscal Year 2014.

cti biopharma corp (CTIC) Key Developments

CTI BioPharma Corp. Appoints Bruce J. Seeley as Executive Vice President and Chief Commercial Officer

CTI BioPharma Corp. announced the appointment of Bruce J. Seeley as Executive Vice President and Chief Commercial Officer, reporting to James Bianco, M.D., CTI BioPharma's President and Chief Executive Officer. Seeley joins CTI BioPharma effective July 27, 2015 and will serve on the executive leadership team, assuming responsibility for CTI BioPharma's commercial organization worldwide - including sales, marketing, commercial operations, medical affairs and supply chain. Seeley most recently served as Senior Vice President and General Manager of Diagnostics at NanoString Technologies Inc. overseeing the launch of the diagnostic product PROSIGNA for early stage breast cancer. In connection with the transition of medical affairs to the new Chief Commercial Officer, Dr. Jack Singer assumes the position of Chief Scientific Officer and will continue to serve as Executive Vice President, Interim Chief Medical Officer and Global Head of Translational Medicine.

CTI BioPharma Corp. Announces Findings from an Investigator-Sponsored Phase 2 Trial in Patients with Either Primary Acute Myeloid Leukemia

CTI BioPharma Corp. announced findings from an investigator-sponsored Phase 2 trial in patients with either primary (de novo) acute myeloid leukemia (AML) or AML that has evolved from myelodysplastic syndrome (MDS). Results showed the combination of tosedostat with low dose cytarabine/Ara-C (LDAC) resulted in an overall response rate (ORR) of 54% in elderly patients with AML with 45% of patients achieving durable complete responses (CR). AML is the most common acute leukemia affecting adults, and its incidence increases with age. AML may develop from the progression of other diseases, such as MDS, which is a blood cancer that also affects the bone marrow and leads to a decrease in circulating red blood cells. Tosedostat is a potential first-in-class selective inhibitor of aminopeptidases, which are required by tumor cells to provide amino acids necessary for growth and tumor cell survival. Final results presented at EHA show that responding patients had a significant improvement in overall survival based on response rates compared to non-responding patients (p=0.018). In the intent-to-treat population (ITT), the ORR was 54% with CR observed in 45% of patients (n=15/33). In the responding patients, the median time for achieving best response was 74 days (range: 22-145 days) and 55% (n=10/18) were still in remission after a median follow-up of 319 days. Safety analysis show that tosedostat in combination with LDAC was generally well tolerated. The primary adverse events observed were pneumonitis (12%), cardiac (6%), brain hemorrhage (3%), and asthenia (3%).

Cell Therapeutics and Baxter Bioscience Report Positive Patient Reported Outcomes from Phase 3 Study of Pacritinib as Treatment for Myelofibrosis

Cell Therapeutics and Baxter International's BioScience business reported positive patient-reported outcome data for pacritinib from the Phase 3 PERSIST-1 study, a randomized, controlled Phase 3 registration-directed trial comparing the efficacy and safety of pacritinib to the best available therapy (BAT) in 327 patients with myelofibrosis, regardless of the patients' platelet counts. Myelofibrosis is a rare blood cancer associated with significantly reduced quality of life and shortened survival. The companies said that results from the study show a significant reduction in the Total Symptom Score (the proportion of patients with a 50% or greater reduction in TSS from baseline to Week 24), and in each individual common disease-related symptom, from baseline to Week 24, in patients treated with pacritinib compared to BAT (exclusive of a JAK inhibitor).


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Price/Book 18.2x
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