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Last $11.00 USD
Change Today -1.02 / -8.49%
Volume 430.7K
As of 8:10 PM 05/22/15 All times are local (Market data is delayed by at least 15 minutes).

calithera biosciences inc (CALA) Snapshot

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12/15/14 - $33.48
52 Week Low
10/10/14 - $6.51
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calithera biosciences inc (CALA) Details

Calithera Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule drugs directed against tumor metabolism and tumor immunology targets for the treatment of cancer in the United States. Its lead product candidate includes CB-839, an inhibitor of glutaminase, which is in three Phase I clinical trials for the treatment of patients with solid tumors, leukemias, lymphomas, and multiple myeloma. The company has a license agreement with Mars, Inc. to develop and commercialize Symbioscience’s portfolio of arginase inhibitors for use in human healthcare. Calithera Biosciences, Inc. was founded in 2010 and is headquartered in South San Francisco, California.

37 Employees
Last Reported Date: 03/27/15
Founded in 2010

calithera biosciences inc (CALA) Top Compensated Officers

Co-Founder, Chief Executive Officer, Presiden...
Total Annual Compensation: $560.0K
Senior Vice President of Development
Total Annual Compensation: $405.0K
Senior Vice President of Drug Discovery
Total Annual Compensation: $405.0K
Senior Vice President of Research
Total Annual Compensation: $364.1K
Compensation as of Fiscal Year 2014.

calithera biosciences inc (CALA) Key Developments

Calithera Biosciences, Inc. Reports Initial Phase I Data for Cb-839 in Patients with Acute Leukemias

Calithera Biosciences, Inc. announced that data from it’s lead, first-in-class program CB-839 will be presented at the 20thCongress of the European Hematology Association (EHA) June 11, 2015 to June 20, 15, 2015, in Vienna, Austria. These preliminary data demonstrate the clinical activity, tolerability and unique mechanism of action of CB-839 in patients with acute leukemia. As of March 1, 2015, fifteen patients with acute myeloid leukemia (AML) had been treated in Calithera's Phase I clinical trial of CB-839 in patients with relapsed or refractory acute leukemias.  Oral CB-839 was administered continuously in 21-day treatment cycles from 100 mg to 1,000 mg three times daily. There were no dose limiting toxicities identified.  Treatment-related adverse events of any grade that occurred in >10% of patients were limited to increases in transaminases (4 patients) and bilirubin (2 patients).  There were no Grade =3 adverse events that were considered treatment-related in >10% of patients. Stable disease for 4-10 cycles was observed in 5 (33%) of 15 efficacy-evaluable AML patients across all dose levels, with patients remaining on study for an average of 134 days (>6 cycles). One of these patients achieved a complete response in the bone marrow with incomplete recovery of peripheral counts (CRi) after 6 cycles of dosing.  All of the patients with stable disease or better were over 65 years of age, and not eligible for high dose therapy.

Calithera Biosciences, Inc. Reports Unaudited Earnings Results for the First Quarter Ended March 31, 2015

Calithera Biosciences, Inc. reported unaudited earnings results for the first quarter ended March 31, 2015. For the quarter, loss from operations was $7,867,000 against $4,150,000 a year ago. Net loss was $7,858,000 against $4,149,000 a year ago.

Calithera Biosciences, Inc. Presents at Bank of America Merrill Lynch 2015 Health Care Conference, May-12-2015 08:00 AM

Calithera Biosciences, Inc. Presents at Bank of America Merrill Lynch 2015 Health Care Conference, May-12-2015 08:00 AM. Venue: Encore at the Wynn, 3131 S Las Vegas Blvd, Las Vegas, Nevada, United States. Speakers: Christopher J. Molineaux, Senior Vice President of Development, Susan M. Molineaux, Co-Founder, Chief Executive Officer, President and Director, William D. Waddill, Chief Financial Officer, Senior Vice President, Treasurer and Secretary.


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