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Last €0.22 EUR
Change Today +0.014 / 6.83%
Volume 875.5K
As of 11:29 AM 07/28/15 All times are local (Market data is delayed by at least 15 minutes).

biotie therapies oyj (BTH1V) Snapshot

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52 Week High
06/22/15 - €0.26
52 Week Low
05/12/15 - €0.14
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Current Stock Chart for BIOTIE THERAPIES OYJ (BTH1V)

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biotie therapies oyj (BTH1V) Details

Biotie Therapies Corp., a drug development company, focuses on the development of drugs for neurodegenerative and psychiatric disorders primarily in Finland and the United States. Its products include Selincro (nalmefene), a dual-acting opioid system modulator that reduces alcohol consumption in alcohol dependent individuals; Tozadenant (SYN115), an oral, potent and selective adenosine A2a receptor antagonist for the treatment of Parkinson’s disease that is in Phase III development; and Nepicastat (SYN117) an orally administered inhibitor for the treatment for cocaine dependence, which has completed in Phase II trial. The company’s products also comprise BTT1023, a monoclonal antibody targeting Vascular Adhesion Protein 1 in Phase II development in fibrotic conditions and received orphan drug designation for the treatment of primary sclerosing cholangitis; and SYN120, an oral, potent, dual antagonist of the 5-HT6 and 5-HT2A receptors that has completed single and multiple ascending dose Phase I clinical studies and a Phase I positron emission tomography imaging study to determine therapeutic dose for subsequent Phase II studies. Biotie Therapies Corp. is based in Turku, Finland.

40 Employees
Last Reported Date: 06/12/15

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biotie therapies oyj (BTH1V) Key Developments

Biotie Announces Start of tozadenant Phase 3 Study in Parkinson's Disease

Biotie announced the start of the Phase 3 clinical study of tozadenant, an investigational adenosine A2a receptor antagonist, in patients with Parkinson's disease (PD) experiencing levodopa related end-of-dose 'wearing-off'. The Phase 3 study (TOZ-PD) is a randomized, double-blind, placebo controlled trial that will evaluate efficacy and safety of tozadenant compared to placebo in 450 PD patients experiencing end-of-dose wearing off episodes. Participants will be randomized to receive twice daily doses of 60 mg or 120 mg of tozadenant or placebo, in addition to their standard anti-PD medications, for 24 weeks. The primary endpoint will be reduction in time spent in the 'off' state in patients taking tozadenant as compared to placebo between baseline and week 24. The placebo-controlled period will be followed by a 52 week open label treatment period to collect additional safety data. Based on current estimates, top-line data from the double-blind portion of the study is expected to be available by the end of 2017.

Biotie Therapies Corp.(NasdaqGS:BITI) added to NASDAQ Composite Index

Biotie Therapies Corp. has been added to Nasdaq Composite Index.

Biotie Therapies Corp. Announces Board Changes

Biotie Therapies Corp. announced that the terms of Don M. Bailey and Mahendra G. Shah as members of Biotie's Board of Directors commence and the number of Board members increases from five to seven. Following the addition of new Board members, the Board of Directors has determined the composition of its committees. Don M. Bailey was elected the Chairman and Bernd Kastler and Merja Karhapaa the members of the Board's Audit Committee. Furthermore, William Burns was elected the Chairman and Guido Magni, Ismail Kola and Mahendra G. Shah the members of the Nomination and Remuneration Committee. The Board of Directors has also elected Bernd Kastler as the Vice Chairman of the Board.


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Price/Sales 9.0x
Price/Book 1.7x
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TEV/Sales 14.9x

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