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Last $26.84 USD
Change Today -0.03 / -0.11%
Volume 153.8K
BPMC On Other Exchanges
As of 8:10 PM 08/28/15 All times are local (Market data is delayed by at least 15 minutes).

blueprint medicines corp (BPMC) Snapshot

Previous Close
Day High
Day Low
52 Week High
06/18/15 - $37.17
52 Week Low
04/30/15 - $18.00
Market Cap
Average Volume 10 Days
Shares Outstanding
Dividend Yield

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blueprint medicines corp (BPMC) Details

Blueprint Medicines Corporation, a biopharmaceutical company, focuses on the development of the highly selective kinase inhibitors for genomically defined cancer subsets. The company’s lead drug candidates include BLU-285, which targets KIT Exon 17 and PDGFRa D842V, abnormally active receptor tyrosine kinase mutants for patients with systemic mastocytosis, a myeloproliferative disorder of the mast cells, and defined subsets of patients with gastrointestinal stromal tumor, as well as targets the KIT D816V mutation; and BLU-554, an orally available, potent, selective, and irreversible inhibitor, which targets FGFR4. It is also developing a drug candidate to target RET, a receptor tyrosine kinase that can becomes abnormally activated when a portion of the gene that encodes RET is joined to part of another gene; and RET resistant mutants that would arise from treatment with first generation therapies, as well as a program that targets rare genetic diseases. The company has a research, development, and commercialization agreement with Alexion Pharma Holding to research, develop, and commercialize drug candidates for an undisclosed activated kinase target, which is the cause of a rare genetic disease. The company was formerly known as Hoyle Pharmaceuticals, Inc. and changed its name to Blueprint Medicines Corporation in June 2011. Blueprint Medicines Corporation was founded in 2008 and is based in Cambridge, Massachusetts.

59 Employees
Last Reported Date: 04/30/15
Founded in 2008

blueprint medicines corp (BPMC) Top Compensated Officers

Chief Executive Officer, President and Direct...
Total Annual Compensation: $311.2K
Co-Founder, Director, Member of Nominating & ...
Total Annual Compensation: --
Chief Business Officer
Total Annual Compensation: $412.5K
Chief Scientific Officer
Total Annual Compensation: $520.0K
Compensation as of Fiscal Year 2014.

blueprint medicines corp (BPMC) Key Developments

Blueprint Medicines Reports Earnings Results for the Second Quarter and Six Months Ended June 30, 2015; Announces Executive Changes

Blueprint Medicines reported earnings results for the second quarter and six months ended June 30, 2015. For the quarter, the company reported collaboration revenues were $2.7 million for the second quarter of 2015. This revenue reflects reimbursement from Alexion for work conducted in the second quarter by Blueprint Medicines under the collaboration, as well as a portion of the $15.0 million upfront payment and $1.8 million milestone payment, which will be amortized over the period of the research term. Net loss was $13.0 million or $0.81 per basic and diluted share in the second quarter, compared to net loss of $8.3 million or $6.99 per basic and diluted share for the same period in 2014. For the six months, the company reported collaboration revenues of $3.33 million. Net loss was $24.552 million against $15.314 million a year ago. The company announced the resignation of Kyle Kuvalanka, Chief Business Officer, who will depart in mid-September. Michael Landsittel, Senior Director of Finance at Blueprint Medicines, will assume the responsibilities of interim Principal Accounting and Financial Officer and will report directly to Mr. Albers.

Blueprint Medicines Corporation Presents at Wedbush PacGrow Healthcare Conference 2015, Aug-11-2015 01:20 PM

Blueprint Medicines Corporation Presents at Wedbush PacGrow Healthcare Conference 2015, Aug-11-2015 01:20 PM. Venue: Le Parker Meridian, 119 West 56th Street, New York, NY 10019, United States. Speakers: Jeffrey W. Albers, Chief Executive Officer, President and Director.

Blueprint Medicines Receives FDA Approval for Investigational New Drug Applications

Blueprint Medicines announced that the U.S. Food and Drug Administration accepted the company's Investigational New Drug (IND) applications to begin Phase 1 clinical trials for its two lead drug candidates: BLU-554 for the treatment of advanced hepatocellular carcinoma (HCC) and cholangiocarcinoma, and BLU-285 for unresectable, treatment-resistant gastrointestinal stromal tumor (GIST). BLU-554 is a potent and selective inhibitor of fibroblast growth factor receptor 4 (FGFR4). Aberrant signaling of FGFR4 is a disease driver in up to 30% of HCC patients and may also play a role in a subset of patients with cholangiocarcinoma, a related cancer of the biliary duct.


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