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Last A$0.48 AUD
Change Today -0.01 / -2.04%
Volume 190.3K
BLT On Other Exchanges
As of 1:10 AM 10/9/15 All times are local (Market data is delayed by at least 15 minutes).

benitec biopharma ltd (BLT) Snapshot

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01/7/15 - A$1.08
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benitec biopharma ltd (BLT) Details

Benitec Biopharma Limited, a biotechnology company, develops treatments for chronic and life-threatening human diseases based on its gene silencing technology, DNA-directed RNA interference (ddRNAi) in Australia. Its in-house development programs include TT-034, which is in Phase I/IIa clinical trials for the treatment of hepatitis C; Hepbarna for the treatment of the hepatitis B virus; Tribetarna for treating drug resistant non-small cell lung cancer; and Pabparna to treat oculopharyngeal muscular dystrophy, an autosomal-dominant inherited, slow-progressing, and late-onset degenerative muscle disorder that occurs at the age of 40 or 50 years in patients, as well as a single dose treatment for wet age-related macular degeneration. The company also licenses its ddRNAi technology to other biopharmaceutical companies for various clinical applications comprising HIV/AIDS, cancer immunotherapy, retinitis pigmentosa, huntington’s diseases, and intractable neuropathic pain. Benitec Biopharma Limited was founded in 1997 and is headquartered in Sydney, Australia.

Founded in 1997

benitec biopharma ltd (BLT) Top Compensated Officers

Chief Executive Officer, Managing Director an...
Total Annual Compensation: A$400.0K
Chief Financial Officer and Company Secretary
Total Annual Compensation: A$230.0K
Chief Business Officer
Total Annual Compensation: A$275.0K
Founding Scientist and Head of Discovery
Total Annual Compensation: A$161.3K
Chief Clinical Officer
Total Annual Compensation: A$83.3K
Compensation as of Fiscal Year 2015.

benitec biopharma ltd (BLT) Key Developments

Benitec Biopharma Limited Presents at Australia Biotech Invest 2015, Oct-06-2015 12:00 PM

Benitec Biopharma Limited Presents at Australia Biotech Invest 2015, Oct-06-2015 12:00 PM. Venue: Crown Conference Centre, Crown Promenade Hotel, Melbourne, Victoria, Australia. Speakers: Georgina Kilfoil, Chief Clinical Officer.

Benitec Biopharma Limited Presents at AusBiotech National Conference 2015, Oct-07-2015 through Oct-09-2015

Benitec Biopharma Limited Presents at AusBiotech National Conference 2015, Oct-07-2015 through Oct-09-2015. Venue: Victoria, Australia. Presentation Date & Speakers: Oct-08-2015, Georgina Kilfoil, Chief Clinical Officer, Sakura Holloway, IP Counsel. Oct-09-2015, Peter Francis, Non-Executive Chairman, Member of Audit & Risk Committee and Member of Remuneration & Nomination Committee.

Benitec Initiates a Fourth Site in Hepatitis C Clinical Trial

Benitec Biopharma Limited announced it has initiated a new site for its ongoing Phase 1/2a TT-034 trial at the Methodist Health System Clinical Research Institute in Dallas, Texas. The site has commenced pre-screening hepatitis C patients and is led by principal investigator Dr. Parvez Mantry. This brings the total number of trial sites to four, with Benitec already having established sites at the Duke Clinical Research Institute, the University of California San Diego and the Texas Liver Institute. More detail on the TT-034 trial: TT-034 is a ddRNAi-based therapeutic, designed to treat and potentially cure hepatitis C (HCV) with a single administration. TT-034 targets the hepatitis C viral RNA at three separate, highly conserved sites. As such it acts as a "triple therapy" even though it is a monotherapy, and minimises the ability of the virus to mutate and escape the therapy. Once it reaches the liver cells it enters the nucleus and produces three separate short hairpin RNAs continuously for the lifetime of the cell. Thus it has the potential to not only treat the existing HCV infection but to guard against reinfection for months to years without the need to re-treat. It has been extensively tested in pre-clinical in vivo studies and no adverse effects were seen at any therapeutic dose. However, as it is regulated as a gene therapy, the trial design is to primarily ensure that treatment with TT-034 is safe, hence the gradual dose escalation.


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